1.0 2009-06-17 23:53:01 UTC 2026-05-14 19:28:38 UTC T3D0942 Carbendazim SmallMolecule Carbendazim belongs to the 2-benzimidazolylcarbamic acid esters, a subclass of benzimidazoles within the organic compounds. This exogenous solid has the formula C9H9N3O2 and an average molecular weight of 191.19 g/mol. It is classified as an organoheterocyclic compound. Carbendazim serves several roles, acting as a fungicide (PMC10979413, PMC11200900, PMC12467741), an agrochemical, and an antinematodal drug. Industrially, it is utilized as a biocide, a preservative, and as processing aids not otherwise specified. It also functions as a pesticide (PMC12452724, PMC10465560, PMC11769159). In the materials sector, it is used in polyvinyl chloride plastics. The compound is released from 41 recorded sources across multiple sectors. These include agriculture and land management via pesticides; drinking water and water supply; household cleaning and consumer products such as soap dispensers, bleaching agents, tobacco pipes, cigar cigarettes, and tobacco smoke filters; building and construction materials including roofs, ceilings, floors, ladders, and sunshades awnings or outside screens; and electrical and electronic equipment including communication cables or conductors, antennas, coils, contacts, and electric hearing aids. It is also found in food, food processing, and cookware, specifically in food contact materials, fermentation processes for beer, molasses and treatment of molasses, and the preparation of malt, wine, or sparkling wine. Exposure occurs through oral, inhalation, and touch routes. Biologically, carbendazim targets the tubulin beta chain (TUBB), the aryl hydrocarbon receptor (AHR), and acts as an agonist of cellular tumor antigen p53 (TP53). Health effects associated with the compound include infertility (PMC12467741). Pesticide Food Toxin Synthetic Toxin Organic Compound Pesticide Ether Carbamate Food Toxin Metabolite Lachrymator Synthetic Compound 1H-Benzimidazol-2-yl-carbamic acid, methyl ester 1H-Benzimidazol-2-ylcarbamic acid methyl ester 1H-Benzimidazol-2-ylcarbamic acid, methyl ester 1H-Benzimidazole-2-carbamic acid, methyl ester 2-(Carbomethoxyamino)benzimidazole 2-(Methoxy-carbonylamino)-benzimidazol 2-(Methoxycarbamoyl)benzimidazole 2-(Methoxycarbonylamino)-benzimidazole 2-(Methoxycarbonylamino)benzimidazole 2-(Methoxycarboxamido)benzimidazole 2-Benzimidazolecarbamic acid, methyl ester 2-Bezimidazolecarbamic acid methyl ester 2-MBC 2-Methyl benzimidazolecarbamate 2-[(Methoxycarbonyl)amino]benzimidazole A 118 (Pesticide) Agrizim Antibac MF Battal Bavistan Bavistin Bavistin 25SD Bavistin 3460 Bavistin 50SD Bavistin FL Bavistine BCM BCM (fungicide) Bengard Benzimidazole carbamate de methyle Benzimidazole-2-carbamic acid, methyl ester Benzimidazolecarbamate methyl ester Benzimidazolecarbamic Bercema-bitosen Bitosen BMC BMC? BMK BMK (fungicide) Carbamic acid, 1H-benzimidazol-2-yl-, methyl ester Carbamic acid, 1H-benzimidazolyl-, methyl ester Carbamic acid, N-1H-benzimidazol-2-yl-, methyl ester Carben VL Carbendazime Carbendazin Carbendazine Carbendazol Carbendazol, JMAF Carbendazole Carbendazym Carbendazyme Custos Delsene Delsene 10 Derosal Derosal 60PM Equitdazin Falicarben Funaben Funaben 3 Funaben 50 Fungisol Fungoxan Garbenda Ipo y Jkatein Jkstein Karben Karben flo stefes Karben stefes flo Kemdazin Kid pest project (carbendazim) (see also carbendazim) Kolfugo Kolfugo 25 FW Kolfugo 25FW Kolfugo extra MBC Mecarzole Medamine Mekarzole Methoxybenzimidazole-2-carbamic acid Methyl 1H-benzimidazol-2-ylcarbamate Methyl 1H-benzimidazol-2-ylcarbamate (9CI) Methyl 1H-benzimidazol-2-ylcarbamate, 9CI Methyl 1H-benzimidazole-2-carbamate Methyl 1H-benzimidazolylcarbamate Methyl 2-benzimidazil carbamate Methyl 2-benzimidazolecarbamate Methyl 2-benzimidazolylcarbamate Methyl benzimidazol-2-ylcarbamate Methyl benzimidazolecarbamate Methyl benzimidazolylcarbamate methyl N-(1H-1,3-benzodiazol-2-yl)carbamate Methyl N-2-benzimidazolecarbamate Methyl-2-benzimidazole carbamate Methyl-N-(2-benzimidazolyl)carbamate Methylbenzimidazole-2-ylcarbamate MYCO Olgin Olgin (fungicide) Pillarstin Preparation G 665 Preventol BCM Protek Sarfun SPIN Spin (pesticide) Stein Stempor Subeej Supercarb Thicoper Triticol Zhiweiling C9H9N3O2 191.1867 191.069476547 methyl N-(1H-1,3-benzodiazol-2-yl)carbamate carbendazim 10605-21-7 COC(=O)NC1=NC2=CC=CC=C2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) TWFZGCMQGLPBSX-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzimidazoles 2-benzimidazolylcarbamic acid esters 2-benzimidazolylcarbamic acid esters Azacyclic compounds Benzenoids Carbamate esters Carbonyl compounds Heteroaromatic compounds Hydrocarbon derivatives Imidazoles Organic carbonic acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds 2-benzimidazolylcarbamic acid ester Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Carbamic acid ester Carbonic acid derivative Carbonyl group Heteroaromatic compound Hydrocarbon derivative Imidazole Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Aromatic heteropolycyclic compounds Carbamate fungicides benzimidazole fungicide benzimidazoles benzimidazolylcarbamate fungicide carbamate ester Detected and Not Quantified Exogenous Cytoplasm Extracellular Membrane Solid White powder. melting_point 302 - 307°C solubility 0.029 mg/mL at 24°C [TOMLIN,C (1994); pH4] logp 1.52 logp 1.46 ALOGPS logs -2.37 ALOGPS solubility 8.25e-01 g/l ALOGPS logp 1.8 ChemAxon pka_strongest_acidic 9.7 ChemAxon pka_strongest_basic 4.28 ChemAxon iupac methyl N-(1H-1,3-benzodiazol-2-yl)carbamate ChemAxon average_mass 191.1867 ChemAxon mono_mass 191.069476547 ChemAxon smiles COC(=O)NC1=NC2=CC=CC=C2N1 ChemAxon formula C9H9N3O2 ChemAxon inchi InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) ChemAxon inchikey TWFZGCMQGLPBSX-UHFFFAOYSA-N ChemAxon polar_surface_area 67.01 ChemAxon refractivity 50.93 ChemAxon polarizability 19.46 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Inhalation (L793) ; oral (L793); dermal (L793) Carbendazim targets beta tubulin in actively dividing cells. It binds to microtubules, interfering with cell functions, such as meiosis and intracellular transportation (A15332). Acute oral LD50 for rats is >15000 mg/kg and >2500 mg/kg for dogs The carbamates are hydrolyzed enzymatically by the liver; degradation products are excreted by the kidneys and the liver. (L793) Acute oral LD50 for rats is >15000 mg/kg and >2500 mg/kg for dogs No indication of carcinogenicity to humans (not listed by IARC). It is a systemic fungicide that is selectively toxic to microorganisms and invertebrates. It is also employed as a casting worm control agent in amenity turf situations such as golf greens and tennis courts. It is also used to control plant diseases in cereals and fruits, including citrus, bananas, strawberries, pineapples, and pomes. The MRLs for fresh produce in the European Union are now between 0.1 and 0.7 mg/kg #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7223254f80> Skin redness and skin irritation. Fetuses exposed to high levels may exhibit microphthalmia (small eyes) or anaphthalmia (no eyes). For acute exposures and first aid: EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. DB13009 HMDB31769 25429 CHEMBL70971 23741 C10897 3392 C006698 Carbendazim 5785 18062653 19049291 Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC. IPCS Intox Database (1987). Antimony pentoxide. : http://www.intox.org/databank/documents/chemical/antpenta/ukpid36.htm Fishel F (2009). Pesticide Toxicity Profile: Carbamate Pesticides. University of Florida, IFAS Extension.: http://edis.ifas.ufl.edu/PI088 BE0000143 BE0003380 AC50 7.36 uM APR_p53Act_72h_up Apredica BE0003721