<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 01:45:28 UTC</creation_date>
  <update_date>2026-05-14 19:51:44 UTC</update_date>
  <accession/>
  <common_name>Ferric chloride</common_name>
  <class>SmallMolecule</class>
  <description>Ferric chloride (Cl3Fe) is an inorganic compound with an average molecular weight of 162.20 g/mol. Ferric chloride belongs to the transition metal chlorides, a subclass of transition metal salts within the inorganic compounds. It is classified as a mixed metal/non-metal compound.

In industrial applications, ferric chloride serves as a catalyst (PMC12848828), a salt (PMC9088909), and a Lewis acid (PMC12226339, PMC5394231). It is further utilized as an astringent, a chemical reaction regulator, a flavouring and nutrient, and as processing aids not otherwise specified (PMC12848828). This compound is released from or found in 39 recorded sources. These include household cleaning and consumer products such as bleaching agents, ash trays, other smoking requisites, cigar cigarettes, and non electric simulated smoking devices. It is found in building and construction materials including tents or canopies, roofs, and fencing, as well as in household items like medals. In the realm of food, food processing and cookware, it is associated with the processing of meats and fermentation processes for beer, wine, sparkling wine, or the preparation of vinegar. Additionally, it is found in electrical and electronic equipment including antennas, communication cables or conductors, contacts, auxiliary devices, and adjustable resistors.

Exposure to ferric chloride is associated with several health effects, including diarrhea (PMC12423868), vomiting (PMC12423868), abdominal pain (PMC12423868), and shock (PMC12423868).</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>Iron trichloride</synonym>
    <synonym>iron(3+) ion trichloride</synonym>
    <synonym>Iron(III) chloride</synonym>
  </synonyms>
  <chemical_formula>Cl3Fe</chemical_formula>
  <average_molecular_weight>162.204</average_molecular_weight>
  <monisotopic_moleculate_weight>160.841500254</monisotopic_moleculate_weight>
  <iupac_name>iron(3+) ion trichloride</iupac_name>
  <traditional_iupac>iron(3+) ion trichloride</traditional_iupac>
  <cas_registry_number>7705-08-0</cas_registry_number>
  <smiles>[Cl-].[Cl-].[Cl-].[Fe+3]</smiles>
  <inchi>InChI=1S/3ClH.Fe/h3*1H;/q;;;+3/p-3</inchi>
  <inchikey>RBTARNINKXHZNM-UHFFFAOYSA-K</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Transition metal salts</class>
    <sub_class>Transition metal chlorides</sub_class>
    <direct_parent>Transition metal chlorides</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic chloride salts</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Inorganic chloride salt</substituent>
      <substituent>Inorganic salt</substituent>
      <substituent>Transition metal chloride</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors>
      <descriptor>iron coordination entity</descriptor>
    </descriptors>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Ferric chloride Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0145257</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>2.3</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-0.77</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>-7</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>iron(3+) ion trichloride</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>162.204</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>160.841500254</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>[Cl-].[Cl-].[Cl-].[Fe+3]</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>Cl3Fe</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/3ClH.Fe/h3*1H;/q;;;+3/p-3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>RBTARNINKXHZNM-UHFFFAOYSA-K</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>1.78</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>-1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7224d5e420&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB15536</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>24380</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
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  <wikipidia/>
  <general_references/>
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</compound>
