1.0 2016-05-19 02:09:21 UTC 2026-05-14 18:07:02 UTC 4-HYDROXYBENZOIC ACID SmallMolecule 4-HYDROXYBENZOIC ACID belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula C7H6O3 and an average molecular weight of 138.12 g/mol. In industrial applications, it serves as a preservative as well as a nutrient and flavouring agent. Additionally, it is present in Polyethylene Terephthalate plastics. The compound is found in or released from five recorded sources, including drinking water and water supply (drinking water), food contact materials within food, food processing and cookware, and building and construction materials such as stairs and ramps. It is also associated with electrical and electronic equipment, specifically antennas and amplifiers. Recorded routes of exposure to the substance include touch, oral, and inhalation. At a molecular level, 4-HYDROXYBENZOIC ACID interacts with four recorded protein targets. It acts as an inhibitor of p-hydroxybenzoate hydroxylase (pobA) and targets Chorismate pyruvate-lyase (ubiC), 4-hydroxybenzoyl-CoA thioesterase (fcbC), and Amine oxidase [flavin-containing] B (MAOB). Benzoic acid, 4-hydroxy- p-Hydroxybenzoic acid C7H6O3 138.122 138.031694053 4-hydroxybenzoic acid P-hydroxybenzoic acid 99-96-7 OC(=O)C1=CC=C(O)C=C1 InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) FJKROLUGYXJWQN-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Hydroxybenzoic acid derivatives 1-hydroxy-2-unsubstituted benzenoids Benzoic acids Benzoyl derivatives Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organooxygen compounds 1-hydroxy-2-unsubstituted benzenoid Aromatic homomonocyclic compound Benzoic acid Benzoyl Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Hydroxybenzoic acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Phenol Aromatic homomonocyclic compounds monohydroxybenzoic acid Detected and Not Quantified logp 1.33 logp 1.58 ALOGPS logs -1.06 ALOGPS solubility 1.19e+01 g/l ALOGPS logp 1.33 ChemAxon pka_strongest_acidic 4.38 ChemAxon pka_strongest_basic -6.1 ChemAxon iupac 4-hydroxybenzoic acid ChemAxon average_mass 138.122 ChemAxon mono_mass 138.031694053 ChemAxon smiles OC(=O)C1=CC=C(O)C=C1 ChemAxon formula C7H6O3 ChemAxon inchi InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) ChemAxon inchikey FJKROLUGYXJWQN-UHFFFAOYSA-N ChemAxon polar_surface_area 57.53 ChemAxon refractivity 35.3 ChemAxon polarizability 12.94 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72747701f8> DB04242 3702506 132 BE0001543 BE0001507 BE0001523 BE0002575 BE0002196