<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 02:12:50 UTC</creation_date>
  <update_date>2026-05-14 16:59:56 UTC</update_date>
  <accession/>
  <common_name>MAGNESIUM OXIDE</common_name>
  <class>SmallMolecule</class>
  <description>MAGNESIUM OXIDE (H2MgO) is an inorganic compound with an average molecular weight of 42.32 g/mol. MAGNESIUM OXIDE belongs to the alkaline earth metal oxides, a subclass of alkaline earth metal organides within the inorganic compounds. It is utilized in plastics such as Polyvinyl Chloride and Polypropylene.

In industrial applications, the compound serves as a binder, filler, catalyst, flux agent, and opacifer (PMC12847695). It is further employed as a pH regulating agent, absorbent, thickening agent, hardener, surface modifier, humectant, drier, anti-caking agent, activator, and as a flavouring and nutrient (PMC12847695). It may also be present as a degradant or impurity (PMC12847695). Regarding its medical utility, it is used as a treatment for breast cancer (PMC6415270).

The compound is found in or released from 58 recorded sources. These include electrical and electronic equipment such as antennas, amplifiers, coils, auxiliary devices, and adjustable resistors. In the realm of building and construction, it is found in roofs, floors, ceilings, fencing, and stairs and ramps. It is associated with household items like watch chains, and household cleaning and consumer products including bleaching agents, ash trays, cigar cigarettes, other smoking requisites, and non electric simulated smoking devices. Within healthcare, pharmaceuticals, and veterinary products, it appears in minerals and drugs for constipation and acid related disorders. Additionally, it is used in food, cookware, and food processing, including the processing of fish and fermentation processes for beer, vinegar, wort, and the preparation of malt. Recorded exposure routes include oral, topical, and irrigation.</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>Magnesium oxide (MgO)</synonym>
  </synonyms>
  <chemical_formula>H2MgO</chemical_formula>
  <average_molecular_weight>42.32</average_molecular_weight>
  <monisotopic_moleculate_weight>41.99560638</monisotopic_moleculate_weight>
  <iupac_name>oxomagnesium</iupac_name>
  <traditional_iupac>magnesium oxide</traditional_iupac>
  <cas_registry_number>1309-48-4</cas_registry_number>
  <smiles>O.[Mg]</smiles>
  <inchi>InChI=1S/Mg.H2O/h;1H2</inchi>
  <inchikey>ZATZOOLBPDMARD-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Alkaline earth metal organides</class>
    <sub_class>Alkaline earth metal oxides</sub_class>
    <direct_parent>Alkaline earth metal oxides</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic oxides</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Alkaline earth metal oxide</substituent>
      <substituent>Inorganic oxide</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Magnesium oxide Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0143734</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-0.57</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-1.1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_basic</kind>
      <value>-0.78</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>oxomagnesium</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>42.32</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>41.99560638</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>O.[Mg]</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>H2MgO</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/Mg.H2O/h;1H2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>ZATZOOLBPDMARD-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>17.07</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>1.44</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>2.88</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7267750478&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB01377</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>14792</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
    <target>
      <target_id/>
      <mechanism_of_action/>
      <constants/>
      <references/>
    </target>
  </targets>
</compound>
