<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 02:12:52 UTC</creation_date>
  <update_date>2026-05-14 19:31:26 UTC</update_date>
  <accession/>
  <common_name>MAGNESIUM SILICATE</common_name>
  <class>SmallMolecule</class>
  <description>Magnesium silicate is an inorganic compound with the formula MgO3Si and an average molecular weight of 100.39 g/mol. MAGNESIUM SILICATE belongs to the alkaline earth metal silicates, a subclass of alkaline earth metal oxoanionic compounds within the inorganic compounds. It is categorized as a mixed metal/non-metal compound.

In industrial applications, magnesium silicate serves several roles, including use as an absorbent, viscosity modifier, opacifer, and filler. It is further utilized as an anti-caking agent and as processing aids not otherwise specified. The compound is found in or released from five recorded sources. These include building and construction materials such as ceilings and fencing, as well as electrical and electronic equipment including antennas and adjustable resistors. Additionally, it is present in healthcare, pharmaceuticals, and veterinary products, specifically within drugs for acid related disorders. The recorded exposure route for this compound is oral.</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>Silicic acid, magnesium salt</synonym>
    <synonym>TALC</synonym>
  </synonyms>
  <chemical_formula>MgO3Si</chemical_formula>
  <average_molecular_weight>100.389</average_molecular_weight>
  <monisotopic_moleculate_weight>99.946712297</monisotopic_moleculate_weight>
  <iupac_name>magnesium(2+) ion oxosilanebis(olate)</iupac_name>
  <traditional_iupac>magnesium(2+) ion oxosilanebis(olate)</traditional_iupac>
  <cas_registry_number>1343-88-0</cas_registry_number>
  <smiles>[Mg++].[O-][Si]([O-])=O</smiles>
  <inchi>InChI=1S/Mg.O3Si/c;1-4(2)3/q+2;-2</inchi>
  <inchikey>FKHIFSZMMVMEQY-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Alkaline earth metal oxoanionic compounds</class>
    <sub_class>Alkaline earth metal silicates</sub_class>
    <direct_parent>Alkaline earth metal silicates</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic oxides</alternative_parent>
      <alternative_parent>Inorganic salts</alternative_parent>
      <alternative_parent>Metalloid salts</alternative_parent>
      <alternative_parent>Miscellaneous silicates</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Alkaline earth metal silicate</substituent>
      <substituent>Inorganic metalloid salt</substituent>
      <substituent>Inorganic oxide</substituent>
      <substituent>Inorganic salt</substituent>
      <substituent>Silicate</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-0.65</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-1.4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>3.84</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>magnesium(2+) ion oxosilanebis(olate)</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>100.389</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>99.946712297</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>[Mg++].[O-][Si]([O-])=O</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>MgO3Si</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/Mg.O3Si/c;1-4(2)3/q+2;-2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>FKHIFSZMMVMEQY-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>63.19</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>4.33</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>4.22</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>-1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226d25790&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB13249</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>72941442</pubchem_compound_id>
  <chembl_id/>
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  <biocyc_id/>
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  <wikipidia/>
  <general_references/>
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</compound>
