1.0 2016-05-19 02:24:51 UTC 2026-05-14 17:50:45 UTC PYRUVALDEHYDE SmallMolecule PYRUVALDEHYDE (C3H4O2) is an organic oxygen compound with an average molecular weight of 72.06 g/mol. PYRUVALDEHYDE belongs to the carbonyl compounds, a subclass of organooxygen compounds within the organic compounds. It is utilized industrially as a nutrient and a flavouring agent. The compound is found in or released from 28 recorded sources. These include drinking water, as well as food, food processing, and cookware sources such as food contact materials, the preparation of vinegar, the preparation of malt, fermentation processes for beer, and food preservation. In household cleaning and consumer products, it is associated with soap detergents, bleaching agents, perfumes within detergents and soaps, cigar cigarettes, and other smoking requisites. It is also found in electrical and electronic equipment, including antennas, amplifiers, electric switches, conductors or conductive bodies characterised by the conductive materials, and cores yokes or armatures. Recorded exposure routes for the compound include touch, oral, and inhalation. PYRUVALDEHYDE has two recorded protein targets: Transient receptor potential cation channel subfamily A member 1 (TRPA1) and Phospholipase A2 (PLA2G1B), for which it acts as an activator or inhibitor. Regarding health effects, the compound serves as a biomarker of cancer (PMC13407726). Additionally, blood levels of PYRUVALDEHYDE are increased in instances of hyperglycemia (PMC9572970) and inflammation (PMC9572970). 2-oxopropanal 2-Oxopropanal Di-substituted propanedione Methyl glyoxal Methylglyoxal methylglyoxal C3H4O2 72.0627 72.021129372 2-oxopropanal methylglyoxal 78-98-8 CC(=O)C=O InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3 AIJULSRZWUXGPQ-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Alpha ketoaldehydes Hydrocarbon derivatives Ketones Organic oxides Short-chain aldehydes Aliphatic acyclic compound Alpha-ketoaldehyde Hydrocarbon derivative Ketone Organic oxide Short-chain aldehyde Aliphatic acyclic compounds 2-oxo aldehyde a ketoaldehyde propanals Detected and Not Quantified Pyruvaldehyde Degradation SMP0000459 Pyruvate Metabolism SMP0000060 Leigh Syndrome SMP0000196 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) SMP0000334 Pyruvate Dehydrogenase Complex Deficiency SMP0000212 Glycine and Serine Metabolism SMP0000004 Dimethylglycine Dehydrogenase Deficiency SMP0000242 Dihydropyrimidine Dehydrogenase Deficiency (DHPD) SMP0000179 Sarcosinemia SMP0000244 Non-Ketotic Hyperglycinemia SMP0000223 Dimethylglycine Dehydrogenase Deficiency SMP0000484 Hyperglycinemia, Non-Ketotic SMP0000485 Primary Hyperoxaluria II, PH2 SMP0000558 Pyruvate Kinase Deficiency SMP0000559 3-Phosphoglycerate Dehydrogenase Deficiency SMP0000721 Dimethylglycine Dehydrogenase Deficiency SMP0125578 Sarcosinemia SMP0125579 Non-Ketotic Hyperglycinemia SMP0125580 3-Phosphoglycerate Dehydrogenase Deficiency SMP0125581 Leigh Syndrome SMP0125770 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) SMP0125771 Pyruvate Dehydrogenase Complex Deficiency SMP0125772 Primary Hyperoxaluria II, PH2 SMP0125773 Pyruvate Kinase Deficiency SMP0125774 logp 0.2 logp -0.38 ALOGPS logs 0.40 ALOGPS solubility 1.80e+02 g/l ALOGPS logp 0.2 ChemAxon pka_strongest_acidic 16.38 ChemAxon pka_strongest_basic -8 ChemAxon iupac 2-oxopropanal ChemAxon average_mass 72.0627 ChemAxon mono_mass 72.021129372 ChemAxon smiles CC(=O)C=O ChemAxon formula C3H4O2 ChemAxon inchi InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3 ChemAxon inchikey AIJULSRZWUXGPQ-UHFFFAOYSA-N ChemAxon polar_surface_area 34.14 ChemAxon refractivity 17.05 ChemAxon polarizability 6.42 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726ca54890> DB03587 880 857 BE0003997 BE0001122