1.0 2016-05-19 02:25:33 UTC 2026-08-20 01:14:19 UTC (1R,2S,5R)-N-(4-METHOXYPHENYL)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANECARBOXAMIDE SmallMolecule (1R,2S,5R)-N-(4-METHOXYPHENYL)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANECARBOXAMIDE belongs to the monoterpenoids, a subclass of prenol lipids within the organic compounds. This compound has the chemical formula C18H27NO2 and an average molecular weight of 289.42 g/mol. In industrial applications, the substance is used as a fragrance, as well as a flavouring and nutrient. It is recorded as being found in or released from eight different sources. These include electrical and electronic equipment, specifically microphones, electric hearing aids, auxiliary devices, and antennas. Additionally, it is found in household cleaning and consumer products, including tobacco product cases, pipe accessories, other smoking requisites, and tobacco product moisture control. Regarding its biological activity, it is a recorded activator of the protein target Transient receptor potential cation channel subfamily M member 8 (TRPM8). C18H27NO2 289.419 289.204179113 (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide (1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexane-1-carboxamide 68489-09-8 [H][C@@]1(C)CC[C@@]([H])(C(C)C)[C@@]([H])(C1)C(=O)NC1=CC=C(OC)C=C1 InChI=1S/C18H27NO2/c1-12(2)16-10-5-13(3)11-17(16)18(20)19-14-6-8-15(21-4)9-7-14/h6-9,12-13,16-17H,5,10-11H2,1-4H3,(H,19,20)/t13-,16+,17-/m1/s1 HNSGVPAAXJJOPQ-XOKHGSTOSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Aromatic monoterpenoids Alkyl aryl ethers Anilides Anisoles Carbonyl compounds Hydrocarbon derivatives Menthane monoterpenoids Methoxyanilines Methoxybenzenes Monocyclic monoterpenoids N-arylamides Organic oxides Organopnictogen compounds Phenoxy compounds Secondary carboxylic acid amides Alkyl aryl ether Anilide Anisole Aromatic homomonocyclic compound Aromatic monoterpenoid Benzenoid Carbonyl group Carboxamide group Carboxylic acid derivative Ether Hydrocarbon derivative Methoxyaniline Methoxybenzene Monocyclic benzene moiety Monocyclic monoterpenoid N-arylamide Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound P-menthane monoterpenoid Phenol ether Phenoxy compound Secondary carboxylic acid amide Aromatic homomonocyclic compounds Detected and Not Quantified logp 4.6 logp 4.68 ALOGPS logs -4.66 ALOGPS solubility 6.38e-03 g/l ALOGPS logp 4.47 ChemAxon pka_strongest_acidic 14.59 ChemAxon pka_strongest_basic -1.8 ChemAxon iupac (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide ChemAxon average_mass 289.419 ChemAxon mono_mass 289.204179113 ChemAxon smiles [H][C@@]1(C)CC[C@@]([H])(C(C)C)[C@@]([H])(C1)C(=O)NC1=CC=C(OC)C=C1 ChemAxon formula C18H27NO2 ChemAxon inchi InChI=1S/C18H27NO2/c1-12(2)16-10-5-13(3)11-17(16)18(20)19-14-6-8-15(21-4)9-7-14/h6-9,12-13,16-17H,5,10-11H2,1-4H3,(H,19,20)/t13-,16+,17-/m1/s1 ChemAxon inchikey HNSGVPAAXJJOPQ-XOKHGSTOSA-N ChemAxon polar_surface_area 38.33 ChemAxon refractivity 86.83 ChemAxon polarizability 34.39 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7224599b18> DB19202 11266244 BE0001186