1.0 2016-05-19 02:25:36 UTC 2026-05-14 17:13:19 UTC RUTIN SmallMolecule RUTIN belongs to the flavonoid glycosides, a subclass of flavonoids within the organic compounds. With an average molecular weight of 610.52 g/mol, RUTIN is a heavy molecule with the formula C27H30O16. Biologically, it functions as a ligand (PMC12540936), an antioxidant (PMC11478989, PMC11548494, PMC11643819, PMC13031289, PMC13470057), and an iron chelator (PMC13470057). In industrial applications, it is used as a stabilizer (PMC9918917) and as a nutrient and flavouring (PMC11478989, PMC11548494, PMC11643819, PMC13031289, PMC13470057). It is further classified biologically as part of the flavonoids (PMC11832627). The compound acts as an inhibitor of Carbonyl reductase [NADPH] 1 (CBR1) and Aldo-keto reductase family 1 member C3 (AKR1C3). RUTIN is found in 36 recorded sources, including healthcare, pharmaceuticals & veterinary products such as medical devices and vasoprotectives; electrical & electronic equipment including batteries, cell phones, capacitors, printed circuit boards, and wires and cables; food, food processing & cookware including the preparation of malt, molasses and treatment of molasses, cellar tools, food packaging, and agglomerated sugar products; building & construction including fencing and ceilings; textiles, leather & furnishings including carpets, rugs, and synthetic textiles; and household cleaning & consumer products such as soap dispensers, other smoking requisites, tobacco product cases, and non electric simulated smoking devices. Exposure routes include oral, inhalation, and touch. The compound exhibits therapeutic effects on inflammation (PMC11478989, PMC12968236, PMC13031289, PMC13470057, PMC3872418), hyperglycemia (PMC12968236, PMC9379957), proteinuria (PMC12968236), and type 2 diabetes mellitus (PMC11478989). It is associated with therapeutic effects on glioblastoma (PMC12466395), colon cancer (PMC6130576), diabetic neuropathy (PMC9423984), anxiety (PMC10831359), seizure (PMC10831359), necrosis (PMC13470057), hypertension (PMC13470057), Alzheimer's disease (PMC13470057), and Parkinson's disease (PMC13470057). Additionally, it is a treatment for hepatic steatosis (PMC13470057), hepatitis (PMC13470057), and hypertension (PMC13470057). PFAS Phytotoxin Quercetin 3-rutinoside Rutin trihydrate Rutoside C27H30O16 610.5175 610.153384912 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one troxerutin 153-18-4 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1 IKGXIBQEEMLURG-NVPNHPEKSA-N Organic compounds Phenylpropanoids and polyketides Flavonoids Flavonoid glycosides Flavonoid-3-O-glycosides 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids 3'-hydroxyflavonoids 4'-hydroxyflavonoids 5-hydroxyflavonoids 7-hydroxyflavonoids Acetals Benzene and substituted derivatives Catechols Chromones Disaccharides Flavones Heteroaromatic compounds Hydrocarbon derivatives O-glycosyl compounds Organic oxides Oxacyclic compounds Oxanes Polyols Pyranones and derivatives Secondary alcohols Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 3'-hydroxyflavonoid 4'-hydroxyflavonoid 5-hydroxyflavonoid 7-hydroxyflavonoid Acetal Alcohol Aromatic heteropolycyclic compound Benzenoid Benzopyran Catechol Chromone Disaccharide Flavone Flavonoid-3-o-glycoside Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Monocyclic benzene moiety O-glycosyl compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Oxane Phenol Polyol Pyran Pyranone Secondary alcohol Vinylogous acid Aromatic heteropolycyclic compounds disaccharide derivative flavonols quercetin O-glucoside rutinoside tetrahydroxyflavone Detected and Not Quantified Rutin Drug Metabolism Action Pathway SMP0143827 logp -0.87 logp 0.15 ALOGPS logs -2.24 ALOGPS solubility 3.54e+00 g/l ALOGPS logp -0.87 ChemAxon pka_strongest_acidic 6.37 ChemAxon pka_strongest_basic -3.7 ChemAxon iupac 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one ChemAxon average_mass 610.5175 ChemAxon mono_mass 610.153384912 ChemAxon smiles C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O ChemAxon formula C27H30O16 ChemAxon inchi InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1 ChemAxon inchikey IKGXIBQEEMLURG-NVPNHPEKSA-N ChemAxon polar_surface_area 265.52 ChemAxon refractivity 140.15 ChemAxon polarizability 57.08 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 16 ChemAxon donor_count 10 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7277749398> DB01698 5280805 4444362 BE0000592 BE0003074