<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 02:26:58 UTC</creation_date>
  <update_date>2026-05-14 19:06:07 UTC</update_date>
  <accession/>
  <common_name>SODIUM SULFATE</common_name>
  <class>SmallMolecule</class>
  <description>SODIUM SULFATE belongs to the alkali metal sulfates, a subclass of alkali metal oxoanionic compounds within the inorganic compounds. It is a mixed metal/non-metal compound with the formula H20Na2O14S and an average molecular weight of 322.19 g/mol. In industrial applications, the compound serves as a pH regulating agent, a flavouring and nutrient, and as processing aids not otherwise specified.

The compound is found in or released from 22 recorded sources. Within electrical and electronic equipment, it is associated with antennas, amplifiers, auxiliary devices, colour television systems, and communication cables or conductors, among five other items. In the category of household cleaning and consumer products, it is found in tobacco product cases, pipe accessories, cigar cigarettes, tobacco product moisture control, and non electric simulated smoking devices. Its presence in food, food processing, and cookware includes the processing of meats, the preparation of vinegar, and fermentation processes for beer. Additionally, it is found in building and construction materials such as ceilings and tents or canopies, as well as healthcare, pharmaceuticals, and veterinary products including minerals and drugs for constipation.

Exposure routes for sodium sulfate include oral, enteral, topical, vaginal, and nasogastric pathways. Regarding its biological activity, there are two recorded protein targets for the compound, acting as an inhibitor of carbonic anhydrase 1 (CA1) and carbonic anhydrase 2 (CA2).</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>Sodium sulfate decahydrate</synonym>
  </synonyms>
  <chemical_formula>H20Na2O14S</chemical_formula>
  <average_molecular_weight>322.195</average_molecular_weight>
  <monisotopic_moleculate_weight>322.036915388</monisotopic_moleculate_weight>
  <iupac_name>disodium decahydrate sulfate</iupac_name>
  <traditional_iupac>disodium decahydrate sulfate</traditional_iupac>
  <cas_registry_number>7727-73-3</cas_registry_number>
  <smiles>O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O</smiles>
  <inchi>InChI=1S/2Na.H2O4S.10H2O/c;;1-5(2,3)4;;;;;;;;;;/h;;(H2,1,2,3,4);10*1H2/q2*+1;;;;;;;;;;;/p-2</inchi>
  <inchikey>RSIJVJUOQBWMIM-UHFFFAOYSA-L</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Alkali metal oxoanionic compounds</class>
    <sub_class>Alkali metal sulfates</sub_class>
    <direct_parent>Alkali metal sulfates</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic oxides</alternative_parent>
      <alternative_parent>Inorganic sodium salts</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Alkali metal sulfate</substituent>
      <substituent>Inorganic oxide</substituent>
      <substituent>Inorganic salt</substituent>
      <substituent>Inorganic sodium salt</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors>
      <descriptor>hydrate</descriptor>
    </descriptors>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Sodium sulfate Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0144492</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-0.84</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-0.84</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>-3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>disodium decahydrate sulfate</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>322.195</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>322.036915388</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>H20Na2O14S</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/2Na.H2O4S.10H2O/c;;1-5(2,3)4;;;;;;;;;;/h;;(H2,1,2,3,4);10*1H2/q2*+1;;;;;;;;;;;/p-2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>RSIJVJUOQBWMIM-UHFFFAOYSA-L</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>80.26</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>11.53</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>5.81</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>-2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf34017e0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB09472</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>62649</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
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  <biocyc_id/>
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  <wikipidia/>
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</compound>
