1.0 2016-05-19 02:29:02 UTC 2026-04-16 22:52:53 UTC TOCOPHEROLS SmallMolecule TOCOPHEROLS (C28H48O2) is a compound with an average molecular weight of 416.68 g/mol. TOCOPHEROLS belongs to the quinone and hydroquinone lipids, a subclass of prenol lipids within the organic compounds. It serves as an industrial flavouring and nutrient, as well as an industrial and biological antioxidant (PMC9439934), and an environmental nutrient (PMC8373945). The compound is found in or released from 23 recorded sources. These include vitamins in healthcare, pharmaceuticals, and veterinary products; food, food processing, and cookware such as the processing of fish and fermentation processes for beer, the preparation of malt, and the preparation of vinegar, wine, or sparkling wine; household cleaning and consumer products including soap detergents, bleaching agents, cigar cigarettes, non-electric simulated smoking devices, and other smoking requisites; building and construction materials such as sunshades, awnings, or outside screens; and electrical and electronic equipment including antennas, communication cables or conductors, cores yokes or armatures, and electrically stimulated smoking devices. Recorded exposure routes include oral, dental, topical, and cutaneous. Health effects associated with TOCOPHEROLS include inflammation (PMC5796020), blood pressure (PMC9818577), arteriosclerosis (PMC9818577), high blood pressure (PMC13074123), hypertension (PMC13074123), and cancer (PMC13074123). Additionally, the compound has demonstrated therapeutic effects on obesity (PMC12897246), chronic inflammation (PMC10745369), and cancer (PMC10384004, PMC11643819, PMC12897246). gamma-Tocopherol Gamma-Tocopherol C28H48O2 416.6795 416.36543078 2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol 2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-1-benzopyran-6-ol 1406-66-2 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=CC(O)=C(C)C(C)=C2O1 InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3 QUEDXNHFTDJVIY-UHFFFAOYSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Quinone and hydroquinone lipids Tocopherols 1-benzopyrans 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Diterpenoids Hydrocarbon derivatives Oxacyclic compounds 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid Alkyl aryl ether Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromane Diterpenoid Ether Hydrocarbon derivative Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Tocopherol Aromatic heteropolycyclic compounds vitamin E Detected and Not Quantified logp 8.81 ALOGPS logs -7.75 ALOGPS solubility 7.37e-06 g/l ALOGPS logp 9.99 ChemAxon pka_strongest_acidic 10.47 ChemAxon pka_strongest_basic -4.9 ChemAxon iupac 2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol ChemAxon average_mass 416.6795 ChemAxon mono_mass 416.36543078 ChemAxon smiles CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=CC(O)=C(C)C(C)=C2O1 ChemAxon formula C28H48O2 ChemAxon inchi InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3 ChemAxon inchikey QUEDXNHFTDJVIY-UHFFFAOYSA-N ChemAxon polar_surface_area 29.46 ChemAxon refractivity 130.33 ChemAxon polarizability 54.13 ChemAxon rotatable_bond_count 12 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226260008> DB11251 14986 14266