1.0 2016-05-19 02:39:14 UTC 2026-05-14 18:45:08 UTC 2-Hydroxyestradiol SmallMolecule 2-Hydroxyestradiol is an organic compound with the formula C18H24O3 and an average molecular weight of 288.38 g/mol. 2-Hydroxyestradiol belongs to the estrane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This substance is recorded as being found in or released from electrical and electronic equipment, specifically antennas and radio transmission systems. Regarding its biological activity, histidine kinase (cyaC) is a recorded protein target for 2-Hydroxyestradiol. The compound is associated with several health effects, including obesity (PMC8632231) and cryptorchidism (PMC4977511). C18H24O3 288.3814 288.172544634 (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-4,5,14-triol (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-4,5,14-triol 362-05-0 [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C(O)=C3 InChI=1S/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1 DILDHNKDVHLEQB-XSSYPUMDSA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Estrane steroids Estrogens and derivatives 1-hydroxy-2-unsubstituted benzenoids 17-hydroxysteroids 3-hydroxysteroids Cyclic alcohols and derivatives Hydrocarbon derivatives Phenanthrenes and derivatives Polyols Secondary alcohols Tetralins 1-hydroxy-2-unsubstituted benzenoid 17-hydroxysteroid 2-hydroxysteroid 3-hydroxysteroid Alcohol Aromatic homopolycyclic compound Benzenoid Cyclic alcohol Estrogen-skeleton Hydrocarbon derivative Hydroxysteroid Organic oxygen compound Organooxygen compound Phenanthrene Polyol Secondary alcohol Tetralin Aromatic homopolycyclic compounds 17beta-hydroxy steroid 2-hydroxy steroid C18 steroids (estrogens) and derivatives C18 steroids (estrogens) and derivatives Estrane and derivatives Detected and Not Quantified Levonorgestrel Action Pathway SMP0125332 Norgestrel Action Pathway SMP0126522 Etonogestrel Action Pathway SMP0126525 Megestrol acetate Action Pathway SMP0126528 Progesterone Action Pathway SMP0126529 Norethisterone Action Pathway SMP0126536 Drospirenone Action Pathway SMP0126538 Norelgestromin Action Pathway SMP0126539 Dienogest Action Pathway SMP0126541 Segesterone acetate Action Pathway SMP0126542 logp 3.44 logp 3.39 ALOGPS logs -3.75 ALOGPS solubility 5.11e-02 g/l ALOGPS logp 3.44 ChemAxon pka_strongest_acidic 9.67 ChemAxon pka_strongest_basic -0.88 ChemAxon iupac (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-4,5,14-triol ChemAxon average_mass 288.3814 ChemAxon mono_mass 288.172544634 ChemAxon smiles [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C(O)=C3 ChemAxon formula C18H24O3 ChemAxon inchi InChI=1S/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1 ChemAxon inchikey DILDHNKDVHLEQB-XSSYPUMDSA-N ChemAxon polar_surface_area 60.69 ChemAxon refractivity 81.89 ChemAxon polarizability 33.08 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f86b0e430c0> DB07706 247304 9303 BE0002733