<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 02:58:04 UTC</creation_date>
  <update_date>2026-08-26 00:26:27 UTC</update_date>
  <accession/>
  <common_name>Triphosphoric acid</common_name>
  <class>SmallMolecule</class>
  <description>Triphosphoric acid is an inorganic compound with the chemical formula H5O10P3 and an average molecular weight of 257.95 g/mol. Triphosphoric acid belongs to the non-metal phosphates, a subclass of non-metal oxoanionic compounds within the inorganic compounds. It is categorized as a homogeneous non-metal compound.

The compound is found in or released from 28 recorded sources across several sectors. In the category of electrical and electronic equipment, it is associated with antennas, coils, conductors or conductive bodies characterised by the conductive materials, cores yokes or armatures, and discharge lamps, among nine others. Within food, food processing and cookware, it is linked to food preservation, the processing of fish, fermentation processes for beer, and the preparation of malt and wort, among two other sources. In household cleaning and consumer products, the compound is found in bleaching agents, soap detergents, perfumes within detergents and soaps, cigar cigarettes, and tobacco product cases, along with one additional source. Furthermore, it is recorded in building and construction materials, specifically ceilings.

Regarding its biological activity, triphosphoric acid has one recorded protein target, which is poly(A) polymerase alpha (PAPOLA).</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>H5O10P3</chemical_formula>
  <average_molecular_weight>257.955</average_molecular_weight>
  <monisotopic_moleculate_weight>257.909555916</monisotopic_moleculate_weight>
  <iupac_name>{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid</iupac_name>
  <traditional_iupac>tripolyphosphate</traditional_iupac>
  <cas_registry_number>10380-08-2</cas_registry_number>
  <smiles>OP(O)(=O)OP(O)(=O)OP(O)(O)=O</smiles>
  <inchi>InChI=1S/H5O10P3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h(H,7,8)(H2,1,2,3)(H2,4,5,6)</inchi>
  <inchikey>UNXRWKVEANCORM-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Homogeneous non-metal compounds</super_class>
    <class>Non-metal oxoanionic compounds</class>
    <sub_class>Non-metal phosphates</sub_class>
    <direct_parent>Non-metal phosphates</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic oxides</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Inorganic oxide</substituent>
      <substituent>Non-metal phosphate</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors>
      <descriptor>acyclic phosphorus acid anhydride</descriptor>
      <descriptor>phosphorus oxoacid</descriptor>
    </descriptors>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Pterine Biosynthesis</name>
      <smpdb_id>SMP0000005</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>DOPA-Responsive Dystonia</name>
      <smpdb_id>SMP0000486</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency</name>
      <smpdb_id>SMP0000487</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps)</name>
      <smpdb_id>SMP0000488</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to DHPR-Deficiency</name>
      <smpdb_id>SMP0000489</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Segawa Syndrome</name>
      <smpdb_id>SMP0000490</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Sepiapterin Reductase Deficiency</name>
      <smpdb_id>SMP0000491</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>DOPA-Responsive Dystonia</name>
      <smpdb_id>SMP0125582</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency</name>
      <smpdb_id>SMP0125583</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps)</name>
      <smpdb_id>SMP0125585</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Hyperphenylalaninemia Due to DHPR-Deficiency</name>
      <smpdb_id>SMP0125586</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Segawa Syndrome</name>
      <smpdb_id>SMP0125587</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Sepiapterin Reductase Deficiency</name>
      <smpdb_id>SMP0125588</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-1.9</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-1.9</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>0.89</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>257.955</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>257.909555916</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>OP(O)(=O)OP(O)(=O)OP(O)(O)=O</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>H5O10P3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/H5O10P3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h(H,7,8)(H2,1,2,3)(H2,4,5,6)</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>UNXRWKVEANCORM-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>170.82</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>36.4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>14.67</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>8</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>5</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>-4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
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  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72269a8fe0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB03896</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>983</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>958</chemspider_id>
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</compound>
