1.0 2016-05-19 03:18:44 UTC 2026-08-18 08:05:15 UTC Sulfapyridine SmallMolecule Sulfapyridine is an organic compound with the chemical formula C11H11N3O2S and an average molecular weight of 249.29 g/mol. Sulfapyridine belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. The compound is found in or released from 37 recorded sources. These include healthcare, pharmaceuticals, and veterinary products such as antibiotics, gynecologicals, and sulfonamides and trimethoprim. It is also present in household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, non-electric simulated smoking devices, and cigar cigarettes. Additional sources include electrical and electronic equipment, such as electric switches, amplifiers, conductors or conductive bodies characterised by the conductive materials, electrically stimulated smoking devices, and electric hearing aids. Environmental sources include drinking water and water supply—specifically tap water, bottled water, desalinated water, and drinking water—as well as aquatic systems and sediments, including seawater, freshwater, surface water, and groundwater. Furthermore, it is found in wastewater, sanitation, and biosolids, including industrial wastewater, mine wastewater, wastewater treatment effluent, and unspecified wastewater, among six more sectors. Recorded exposure routes for sulfapyridine include oral, inhalation, and touch. Regarding its biological activity, there are two recorded protein targets for the compound: it acts as an inhibitor of dihydropteroate synthase type-1 (sulI) and dihydropteroate synthase (folP). PMT C11H11N3O2S 249.289 249.057197301 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide ronin 144-83-2 NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1 InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14) GECHUMIMRBOMGK-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Aminobenzenesulfonamides Aminosulfonyl compounds Aniline and substituted anilines Azacyclic compounds Benzenesulfonyl compounds Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Organic oxides Organopnictogen compounds Organosulfonamides Primary amines Pyridines and derivatives Amine Aminobenzenesulfonamide Aminosulfonyl compound Aniline or substituted anilines Aromatic heteromonocyclic compound Azacycle Benzenesulfonyl group Heteroaromatic compound Hydrocarbon derivative Imidolactam Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Organosulfonic acid amide Organosulfonic acid or derivatives Organosulfur compound Primary amine Pyridine Sulfonyl Aromatic heteromonocyclic compounds pyridines substituted aniline sulfonamide sulfonamide antibiotic Detected and Not Quantified Sulfasalazine Action Pathway SMP0126115 Sulfapyridine Drug Metabolism Action Pathway SMP0143325 logp 1.01 logp 0.84 ALOGPS logs -3.03 ALOGPS solubility 2.35e-01 g/l ALOGPS logp 1.01 ChemAxon pka_strongest_acidic 6.24 ChemAxon pka_strongest_basic 2.63 ChemAxon iupac 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide ChemAxon average_mass 249.289 ChemAxon mono_mass 249.057197301 ChemAxon smiles NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1 ChemAxon formula C11H11N3O2S ChemAxon inchi InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14) ChemAxon inchikey GECHUMIMRBOMGK-UHFFFAOYSA-N ChemAxon polar_surface_area 85.08 ChemAxon refractivity 65.75 ChemAxon polarizability 24.97 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bae65d0d8> DB00891 5336 5145 BE0000120 BE0000803