1.0 2016-05-19 03:56:03 UTC 2026-05-14 16:54:51 UTC Retinoic acid, 13-cis- SmallMolecule Retinoic acid, 13-cis- belongs to the retinoids, a subclass of prenol lipids within the organic compounds. This compound, which falls under the superclass of lipids and lipid-like molecules, has the chemical formula C20H28O2 and an average molecular weight of 300.44 g/mol. It is used for industrial pharmaceutical purposes. The compound is found in seven recorded sources, including anti-acne preparations within healthcare, pharmaceuticals, and veterinary products. It is also present in floors used in building and construction, line transmission systems in electrical and electronic equipment, and the preparation of vinegar in food, food processing, and cookware. Additionally, it is found in household cleaning and consumer products, specifically other smoking requisites, pipe accessories, and non-electric simulated smoking devices. Recorded exposure routes for this substance include topical and oral administration. Regarding its biological activity, retinoic acid, 13-cis- has two recorded protein targets. It acts as an agonist for both the retinoic acid receptor alpha (RARA) and the retinoic acid receptor gamma (RARG), although its interaction with RARG is also categorized as other/unknown. 13-cis Retinoic acid 13-cis-Retinoic acid ISOTRETINOIN C20H28O2 300.4351 300.20893014 (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid isotretinoin 4759-48-2 C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C\C(O)=O InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- SHGAZHPCJJPHSC-XFYACQKRSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Retinoids Retinoids Carbonyl compounds Carboxylic acids Diterpenoids Hydrocarbon derivatives Medium-chain fatty acids Methyl-branched fatty acids Monocarboxylic acids and derivatives Organic oxides Unsaturated fatty acids Aliphatic homomonocyclic compound Branched fatty acid Carbonyl group Carboxylic acid Carboxylic acid derivative Diterpenoid Fatty acid Fatty acyl Hydrocarbon derivative Medium-chain fatty acid Methyl-branched fatty acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Retinoic acid Retinoid skeleton Unsaturated fatty acid Aliphatic homomonocyclic compounds Retinoids retinoic acid Detected and Not Quantified 13-cis-Retinoic acid Drug Metabolism Pathway SMP0145343 logp 5.01 logp 5.66 ALOGPS logs -4.80 ALOGPS solubility 4.77e-03 g/l ALOGPS logp 5.01 ChemAxon pka_strongest_acidic 5 ChemAxon iupac (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid ChemAxon average_mass 300.4351 ChemAxon mono_mass 300.20893014 ChemAxon smiles C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C\C(O)=O ChemAxon formula C20H28O2 ChemAxon inchi InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- ChemAxon inchikey SHGAZHPCJJPHSC-XFYACQKRSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 97.79 ChemAxon polarizability 36.15 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726c8aff08> DB00982 5282379 4445539 BE0000663 BE0000144