<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 04:00:24 UTC</creation_date>
  <update_date>2026-05-14 19:08:04 UTC</update_date>
  <accession/>
  <common_name>Decamethylcyclopentasiloxane</common_name>
  <class>SmallMolecule</class>
  <description>Decamethylcyclopentasiloxane (C10H30O5Si5) is a compound with an average molecular weight of 370.77 g/mol. Decamethylcyclopentasiloxane belongs to the organosilicon compounds, a subclass of organometalloid compounds within the organic compounds. In industrial applications, it serves as a solvent, diluent, surface modifier, and film former. It is further utilized as a fragrance, a softener and conditioner, and as processing aids not otherwise specified.

The compound is found in or released from 27 recorded sources. These include electrical and electronic equipment, such as amplifiers, antennas, cores yokes or armatures, discharge lamps, and conductors or conductive bodies characterised by the conductive materials. Within household cleaning and consumer products, it is present in bleaching agents, cigar cigarettes, non electric simulated smoking devices, soap detergents, and perfumes within detergents and soaps. Its presence in food, food processing, and cookware is noted in food contact materials, food preservation, the processing of meats, and the preparation of vinegar. Additionally, it is found in building and construction materials, specifically ceilings and fencing, as well as in drinking water and water supply. Recorded exposure routes include touch, oral, and inhalation. Literature support specifically documents inhalation as an exposure route (PMC2721671, PMC9855567).</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>Cyclopentasiloxane, decamethyl-</synonym>
    <synonym>decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane</synonym>
  </synonyms>
  <chemical_formula>C10H30O5Si5</chemical_formula>
  <average_molecular_weight>370.77</average_molecular_weight>
  <monisotopic_moleculate_weight>370.093956741</monisotopic_moleculate_weight>
  <iupac_name>decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane</iupac_name>
  <traditional_iupac>decamethylcyclopentasiloxane</traditional_iupac>
  <cas_registry_number>541-02-6</cas_registry_number>
  <smiles>C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1</smiles>
  <inchi>InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3</inchi>
  <inchikey>XMSXQFUHVRWGNA-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Organic compounds</kingdom>
    <super_class>Organometallic compounds</super_class>
    <class>Organometalloid compounds</class>
    <sub_class>Organosilicon compounds</sub_class>
    <direct_parent>Organoheterosilanes</direct_parent>
    <alternate_parents>
      <alternative_parent>Hydrocarbon derivatives</alternative_parent>
      <alternative_parent>Organic metalloid salts</alternative_parent>
      <alternative_parent>Organic oxygen compounds</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Aliphatic heteromonocyclic compound</substituent>
      <substituent>Hydrocarbon derivative</substituent>
      <substituent>Organic metalloid salt</substituent>
      <substituent>Organic oxygen compound</substituent>
      <substituent>Organic salt</substituent>
      <substituent>Organoheterosilane</substituent>
    </substituents>
    <molecular_framework>Aliphatic heteromonocyclic compounds</molecular_framework>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>0.96</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>4.08</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logs</kind>
      <value>-4.66</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>solubility</kind>
      <value>8.03e-03 g/l</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logp</kind>
      <value>0.96</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_basic</kind>
      <value>-3.3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>370.77</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>370.093956741</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C10H30O5Si5</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>XMSXQFUHVRWGNA-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>46.15</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>66.21</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>35.14</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>5</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226879890&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB11244</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>10913</pubchem_compound_id>
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</compound>
