<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-19 04:42:21 UTC</creation_date>
  <update_date>2026-05-14 19:41:15 UTC</update_date>
  <accession/>
  <common_name>Hypochlorous acid</common_name>
  <class>SmallMolecule</class>
  <description>Hypochlorous acid (ClHO) is an inorganic compound with an average molecular weight of 52.46 g/mol. Hypochlorous acid belongs to the non-metal hypochlorites, a subclass of non-metal oxoanionic compounds within the inorganic compounds. Industrially, this compound is utilized as a biocide, pharmaceutical, oxidizing agent, and deodorizer.

The compound is identified in 33 recorded sources. These include household cleaning and consumer products such as soap dispensers, bleaching agents, cigar cigarettes, non electric simulated smoking devices, and pipe accessories. It is found in building and construction materials, specifically tents or canopies, floors, and ceilings. Within the food, food processing and cookware sector, it is associated with the preparation of malt, wort, and vinegar, as well as fermentation processes for beer and the preparation of wine or sparkling wine. Additionally, it is released from electrical and electronic equipment, including antennas, colour television systems, communication cables or conductors, contacts, and cores yokes or armatures.

Regarding health effects, hypochlorous acid is associated with cancer (PMC11729017) and inflammation (PMC11678264, PMC5970065, PMC7932781). Conversely, it is also used as a treatment for inflammation (PMC11246752).</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>ClHO</chemical_formula>
  <average_molecular_weight>52.46</average_molecular_weight>
  <monisotopic_moleculate_weight>51.971592361</monisotopic_moleculate_weight>
  <iupac_name>hypochlorous acid</iupac_name>
  <traditional_iupac>hypochlorous acid</traditional_iupac>
  <cas_registry_number>7790-92-3</cas_registry_number>
  <smiles>OCl</smiles>
  <inchi>InChI=1S/ClHO/c1-2/h2H</inchi>
  <inchikey>QWPPOHNGKGFGJK-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Homogeneous non-metal compounds</super_class>
    <class>Non-metal oxoanionic compounds</class>
    <sub_class>Non-metal hypochlorites</sub_class>
    <direct_parent>Non-metal hypochlorites</direct_parent>
    <alternate_parents/>
    <substituents>
      <substituent>Non-metal hypochlorite</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors>
      <descriptor>an inorganic compound</descriptor>
      <descriptor>chlorine oxoacid</descriptor>
      <descriptor>reactive oxygen species</descriptor>
    </descriptors>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>0.32</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-0.37</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logs</kind>
      <value>0.99</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>solubility</kind>
      <value>5.12e+02 g/l</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logp</kind>
      <value>0.32</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>7.93</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_basic</kind>
      <value>-5.9</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>hypochlorous acid</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>52.46</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>51.971592361</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>OCl</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>ClHO</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/ClHO/c1-2/h2H</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>QWPPOHNGKGFGJK-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>20.23</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>8.7</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>3.49</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baf7247e0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB14135</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>24341</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets/>
</compound>
