1.0 2016-05-19 04:43:57 UTC 2026-08-18 15:49:21 UTC Bisphenol S SmallMolecule Bisphenol S (C12H10O4S) is an organic compound with an average molecular weight of 250.27 g/mol. Bisphenol S belongs to the benzenesulfonyl compounds, a subclass of benzene and substituted derivatives within the organic compounds. It is used in unspecified polycarbonate plastics. Biologically, the compound acts as an endocrine disruptor (PMC10049369), xenoestrogen (PMC5460783), toxin (PMC10049369), poison (PMC10538013), and agonist (PMC13286685). The compound is released from 32 recorded sources, including drinking water, indoor air, and building and construction materials such as floors, tents or canopies. It is found in food contact materials, food preservation, and fish processing, as well as household cleaning and consumer products including soap detergents, bleaching agents, perfumes within detergents and soaps, cigar cigarettes, and tobacco smoke filters. Additional sources include electrical and electronic equipment such as antennas, amplifiers, communication cables or conductors, coils, and conductors or conductive bodies characterised by the conductive materials. Recorded exposure routes include oral, touch, and inhalation, with literature support for inhalation (PMC9622783). Bisphenol S is associated with several health effects, including obesity (PMC10477371, PMC10538013, PMC10591514, PMC11938062, PMC12751047, PMC5974368, PMC6944215, PMC7210526, PMC7983487, PMC9229358), weight gain (PMC8669078), and increase in diabetes mellitus (PMC11267006). It is linked to kidney disease (PMC12812235), hyperuricemia (PMC13307085), anemia increase (PMC12000553), and blood pressure increase (PMC7354351). Other associated conditions include heart disease, cancer, and asthma (PMC9918139), as well as asthma (PMC12441581). Reproductive and mental health effects include infertility (PMC12734433), male infertility (PMC11672798), ovarian dysfunction (PMC13286685), anxiety, depression, and hyperactivity (PMC12523086). It is associated with breast cancer (PMC12649852) and an increase in breast cancer (PMC13101310, PMC5260492). Additionally, the compound is elevated in blood in cases of cryptorchidism (PMC8654277). Phenolic Antioxidant 4,4'-Sulfonyldiphenol 4,4'-sulphonyldiphenol 4-(4-hydroxybenzenesulfonyl)phenol Phenol, 4,4'-sulfonylbis- C12H10O4S 250.27 250.029979976 4-(4-hydroxybenzenesulfonyl)phenol bisphenol S 80-09-1 OC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(O)C=C1 InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H VPWNQTHUCYMVMZ-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonyl compounds Benzenesulfonyl compounds 1-hydroxy-2-unsubstituted benzenoids Hydrocarbon derivatives Organic oxides Organooxygen compounds Sulfones 1-hydroxy-2-unsubstituted benzenoid Aromatic homomonocyclic compound Benzenesulfonyl group Hydrocarbon derivative Organic oxide Organic oxygen compound Organooxygen compound Organosulfur compound Phenol Sulfone Sulfonyl Aromatic homomonocyclic compounds phenols sulfone Detected and Not Quantified logp 1.9 logp 1.89 ALOGPS logs -2.61 ALOGPS solubility 6.11e-01 g/l ALOGPS logp 2.32 ChemAxon pka_strongest_acidic 7.42 ChemAxon pka_strongest_basic -6.6 ChemAxon iupac 4-(4-hydroxybenzenesulfonyl)phenol ChemAxon average_mass 250.27 ChemAxon mono_mass 250.029979976 ChemAxon smiles OC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(O)C=C1 ChemAxon formula C12H10O4S ChemAxon inchi InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H ChemAxon inchikey VPWNQTHUCYMVMZ-UHFFFAOYSA-N ChemAxon polar_surface_area 74.6 ChemAxon refractivity 63.55 ChemAxon polarizability 24.11 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f722103b228> 6626 6374