1.0 2016-05-20 14:52:34 UTC 2026-05-14 16:37:31 UTC Phenylpropanolamine SmallMolecule Phenylpropanolamine is an organic compound with the chemical formula C9H13NO and an average molecular weight of 151.21 g/mol. Phenylpropanolamine belongs to the phenylpropanes, a subclass of benzene and substituted derivatives within the organic compounds. It is classified under the superclass of benzenoids. The compound has been identified in or released from 22 recorded sources across several categories. Within healthcare, pharmaceuticals, and veterinary products, it is found in nasal preparations. In the sector of food, food processing, and cookware, it is associated with the preparation of malt and fermentation processes for beer. Its presence is also recorded in building and construction materials, specifically tents or canopies, roofs, and fencing. Additionally, it is found in household cleaning and consumer products, including tobacco smoke filters, tobacco product cases, pipe accessories, other smoking requisites, and cigar cigarettes. It is further identified in electrical and electronic equipment, such as electrically stimulated smoking devices, electric switches, communication cables or conductors, antennas, fixed capacitors and their manufacture, and six other sources. Regarding its biological activity, phenylpropanolamine acts as an agonist, inhibitor, or partial agonist for seven recorded protein targets. These include the D(1A) dopamine receptor (DRD1), the Beta-1 adrenergic receptor (ADRB1), the Beta-2 adrenergic receptor (ADRB2), the Alpha-2A adrenergic receptor (ADRA2A), and three other proteins. The recorded route of exposure for this compound is oral. Norephedrine C9H13NO 151.2056 151.099714043 (1S,2R)-2-amino-1-phenylpropan-1-ol phenylpropanolamine 14838-15-4 C[C@@H](N)[C@@H](O)C1=CC=CC=C1 InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1 DLNKOYKMWOXYQA-VXNVDRBHSA-N Organic compounds Benzenoids Benzene and substituted derivatives Phenylpropanes Phenylpropanes 1,2-aminoalcohols Aralkylamines Aromatic alcohols Hydrocarbon derivatives Monoalkylamines Organopnictogen compounds Secondary alcohols 1,2-aminoalcohol Alcohol Amine Aralkylamine Aromatic alcohol Aromatic homomonocyclic compound Hydrocarbon derivative Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenylpropane Primary aliphatic amine Primary amine Secondary alcohol Aromatic homomonocyclic compounds amphetamines Detected and Not Quantified Phenylpropanolamine Drug Metabolism Action Pathway SMP0142854 logp 0.89 logp 0.57 ALOGPS logs -0.87 ALOGPS solubility 2.06e+01 g/l ALOGPS logp 0.89 ChemAxon pka_strongest_acidic 13.9 ChemAxon pka_strongest_basic 9.37 ChemAxon iupac (1S,2R)-2-amino-1-phenylpropan-1-ol ChemAxon average_mass 151.2056 ChemAxon mono_mass 151.099714043 ChemAxon smiles C[C@@H](N)[C@@H](O)C1=CC=CC=C1 ChemAxon formula C9H13NO ChemAxon inchi InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1 ChemAxon inchikey DLNKOYKMWOXYQA-VXNVDRBHSA-N ChemAxon polar_surface_area 46.25 ChemAxon refractivity 44.91 ChemAxon polarizability 16.98 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 2 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf330fd28> DB00397 26934 25082 BE0000020 BE0000172 BE0000694 BE0000289 BE0000572 BE0000342 BE0002449