1.0 2016-05-20 16:11:54 UTC 2026-08-18 09:32:00 UTC Sulfafurazole (Sulfisoxazole) SmallMolecule Sulfafurazole (Sulfisoxazole) belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula C11H13N3O3S and an average molecular weight of 267.30 g/mol. In terms of biological activity, it functions as an inhibitor of the protein target Dihydropteroate synthase (folP). The compound is associated with 22 recorded sources across diverse sectors. Within healthcare, pharmaceuticals, and veterinary products, it is found in antibiotics, antiinfectives, gynecologicals, and sulfonamides and trimethoprim. It is also released from food, food processing, and cookware sources, including meat processing, food preservation, and fermentation processes for beer, as well as the preparation of wort and wine or sparkling wine. In the category of household cleaning and consumer products, it appears in soap detergents, perfumes within detergents and soaps, non-electric simulated smoking devices, and tobacco smoke filters. Additionally, it is recorded in building and construction materials, specifically ceilings, and electrical and electronic equipment, including antennas, conductors or conductive bodies characterised by the conductive materials, electrodes, hybrid capacitors, and electrically stimulated smoking devices. Recorded exposure routes for this compound include oral and inhalation. 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide sulfisoxazole Sulfisoxazole C11H13N3O3S 267.304 267.067761987 4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide ganda 127-69-5 CC1=NOC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1C InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3 NHUHCSRWZMLRLA-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Aminobenzenesulfonamides Aminosulfonyl compounds Aniline and substituted anilines Azacyclic compounds Benzenesulfonyl compounds Heteroaromatic compounds Hydrocarbon derivatives Isoxazoles Organic oxides Organooxygen compounds Organopnictogen compounds Organosulfonamides Oxacyclic compounds Primary amines Amine Aminobenzenesulfonamide Aminosulfonyl compound Aniline or substituted anilines Aromatic heteromonocyclic compound Azacycle Azole Benzenesulfonyl group Heteroaromatic compound Hydrocarbon derivative Isoxazole Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfonic acid amide Organosulfonic acid or derivatives Organosulfur compound Oxacycle Primary amine Sulfonyl Aromatic heteromonocyclic compounds isoxazoles sulfonamide sulfonamide antibiotic Detected and Not Quantified Sulfisoxazole Drug Metabolism Action Pathway SMP0142724 logp 0.73 logp 1.14 ALOGPS logs -2.93 ALOGPS solubility 3.13e-01 g/l ALOGPS logp 0.73 ChemAxon pka_strongest_acidic 5.8 ChemAxon pka_strongest_basic 2.17 ChemAxon iupac 4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide ChemAxon average_mass 267.304 ChemAxon mono_mass 267.067761987 ChemAxon smiles CC1=NOC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1C ChemAxon formula C11H13N3O3S ChemAxon inchi InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3 ChemAxon inchikey NHUHCSRWZMLRLA-UHFFFAOYSA-N ChemAxon polar_surface_area 98.22 ChemAxon refractivity 67.92 ChemAxon polarizability 26.93 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bd3ddc0a0> DB00263 5344 5151 BE0000803