<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-20 16:16:46 UTC</creation_date>
  <update_date>2026-05-14 19:06:22 UTC</update_date>
  <accession/>
  <common_name>Talc-based body powder (perineal use of)</common_name>
  <class>SmallMolecule</class>
  <description>Talc-based body powder (perineal use of) belongs to the alkaline earth metal fluorides, a subclass of alkaline earth metal salts within the inorganic compounds. This compound is characterized by the formula F2Mg and has an average molecular weight of 62.30 g/mol. It is categorized within the superclass of mixed metal/non-metal compounds.

In industrial contexts, this substance serves a wide variety of roles and uses. It is utilized as an abrasive, absorbent, humectant, opacifer, filler, and anti-caking agent. Additionally, it functions as a pigment, surface modifier, flow promoter, and flux agent. It is also employed as an adhesion/cohesion promoter, thickening agent, cleaning agent, and as a flavouring and nutrient. It is further categorized as a processing aid not otherwise specified.

Talc-based body powder (perineal use of) is found in or released from 21 recorded sources across several sectors. Within electrical and electronic equipment, it is associated with antennas, adjustable resistors, coils, auxiliary devices, and communication cables or conductors, among five other items. In building and construction, it is present in roofs, ceilings, floors, fencing, and stairs and ramps, along with two other sources. In the category of household cleaning and consumer products, it is found in soap dispensers and pipe accessories. Furthermore, it is released from household items such as rosaries and is used in food, food processing and cookware specifically for processing fish.</description>
  <categories/>
  <types>
    <type>Human Neurotoxin</type>
  </types>
  <synonyms>
    <synonym>Talc</synonym>
  </synonyms>
  <chemical_formula>F2Mg</chemical_formula>
  <average_molecular_weight>62.302</average_molecular_weight>
  <monisotopic_moleculate_weight>61.98184803</monisotopic_moleculate_weight>
  <iupac_name>magnesium(2+) ion difluoride</iupac_name>
  <traditional_iupac>magnesium(2+) ion difluoride</traditional_iupac>
  <cas_registry_number>14807-96-6</cas_registry_number>
  <smiles>[F-].[F-].[Mg++]</smiles>
  <inchi>InChI=1S/2FH.Mg/h2*1H;/q;;+2/p-2</inchi>
  <inchikey>ORUIBWPALBXDOA-UHFFFAOYSA-L</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Alkaline earth metal salts</class>
    <sub_class>Alkaline earth metal fluorides</sub_class>
    <direct_parent>Alkaline earth metal fluorides</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic salts</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Alkaline earth metal fluoride</substituent>
      <substituent>Inorganic salt</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Talc Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0144513</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-0.65</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>0.15</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_acidic</kind>
      <value>3.17</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>magnesium(2+) ion difluoride</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>62.302</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>61.98184803</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>[F-].[F-].[Mg++]</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>F2Mg</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/2FH.Mg/h2*1H;/q;;+2/p-2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>ORUIBWPALBXDOA-UHFFFAOYSA-L</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>0.87</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>0.44</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>-1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7279b4a1e8&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB09511</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>16211421</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
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</compound>
