1.0 2016-05-22 03:30:21 UTC 2026-08-19 01:53:31 UTC Probenecid SmallMolecule Probenecid (C13H19NO4S) is a compound with an average molecular weight of 285.36 g/mol. Probenecid belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. It is utilized as a treatment for hyperuricemia (PMC10346988). The compound is found in or released from 45 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is associated with antigout preparations and gynecologicals. It is also recorded in building and construction materials such as floors and ceilings, household items including coins, and food, food processing, and cookware categories including food preservation, processing meats, processing fish, preparation of wort, and fermentation processes for beer. Additionally, it is found in household cleaning and consumer products, such as soap detergents, perfumes within detergents and soaps, other smoking requisites, non electric simulated smoking devices, and cigar cigarettes. It is further linked to electrical and electronic equipment, including antennas, amplifiers, communication cables or conductors, colour television systems, auxiliary devices, and 23 other sources. The recorded exposure route for probenecid is oral. The compound interacts with five recorded protein targets, acting as an antagonist, inhibitor, or inhibitory allosteric modulator of pannexin-1 (PANX1), organic anion transporter 3 (SLC22A8), solute carrier family 22 member 6 (SLC22A6), solute carrier family 22 member 11 (SLC22A11), and one other protein. 4-(dipropylsulfamoyl)benzoic acid C13H19NO4S 285.359 285.103478791 4-(dipropylsulfamoyl)benzoic acid probenecid 57-66-9 CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) DBABZHXKTCFAPX-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Benzenesulfonamides Aminosulfonyl compounds Benzenesulfonyl compounds Benzoic acids Benzoyl derivatives Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Organosulfonamides Aminosulfonyl compound Aromatic homomonocyclic compound Benzenesulfonamide Benzenesulfonyl group Benzoic acid Benzoic acid or derivatives Benzoyl Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfonic acid amide Organosulfonic acid or derivatives Organosulfur compound Sulfonyl Aromatic homomonocyclic compounds benzoic acids sulfonamide Detected and Not Quantified Probenecid Drug Metabolism Action Pathway SMP0143461 logp 2.44 logp 1.52 ALOGPS logs -2.83 ALOGPS solubility 4.25e-01 g/l ALOGPS logp 2.44 ChemAxon pka_strongest_acidic 3.53 ChemAxon iupac 4-(dipropylsulfamoyl)benzoic acid ChemAxon average_mass 285.359 ChemAxon mono_mass 285.103478791 ChemAxon smiles CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O ChemAxon formula C13H19NO4S ChemAxon inchi InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) ChemAxon inchikey DBABZHXKTCFAPX-UHFFFAOYSA-N ChemAxon polar_surface_area 74.68 ChemAxon refractivity 73.81 ChemAxon polarizability 29.96 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727f030d38> DB01032 4911 4742 BE0003645 BE0000879 BE0001066 BE0003719 BE0009016