1.0 2016-05-22 03:37:01 UTC 2026-08-22 21:11:30 UTC Amifostine SmallMolecule Amifostine is an organic compound with the formula C5H15N2O3PS and an average molecular weight of 214.22 g/mol. Amifostine belongs to the organothiophosphorus compounds, a class of organophosphorus compounds within the organic compounds. It is recorded as being released from healthcare, pharmaceuticals & veterinary products, specifically unclassified therapeutic products, and is administered via intravenous exposure. Regarding its biological activity, amifostine acts as an inducer of the protein target Alkaline phosphatase, germ cell type (ALPG). C5H15N2O3PS 214.223 214.054099558 ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid amifostine 20537-88-6 NCCCNCCSP(O)(O)=O InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10) JKOQGQFVAUAYPM-UHFFFAOYSA-N Organic compounds Organophosphorus compounds Organothiophosphorus compounds Organothiophosphorus compounds Dialkylamines Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Sulfenyl compounds Aliphatic acyclic compound Amine Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organopnictogen compound Organosulfur compound Organothiophosphorus compound Primary aliphatic amine Primary amine Secondary aliphatic amine Secondary amine Sulfenyl compound Aliphatic acyclic compounds diamine organic thiophosphate Detected and Not Quantified Amifostine Drug Metabolism SMP0130669 Amifostine Drug Metabolism Action Pathway SMP0143563 logp -3.7 logp -1.44 ALOGPS logs -1.06 ALOGPS solubility 1.87e+01 g/l ALOGPS logp -3.7 ChemAxon pka_strongest_acidic 2.06 ChemAxon pka_strongest_basic 11.01 ChemAxon iupac ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid ChemAxon average_mass 214.223 ChemAxon mono_mass 214.054099558 ChemAxon smiles NCCCNCCSP(O)(O)=O ChemAxon formula C5H15N2O3PS ChemAxon inchi InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10) ChemAxon inchikey JKOQGQFVAUAYPM-UHFFFAOYSA-N ChemAxon polar_surface_area 95.58 ChemAxon refractivity 51.28 ChemAxon polarizability 21.01 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 5 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72673f3a28> DB01143 29927142 2056 BE0000896