1.0 2016-05-22 03:37:09 UTC 2026-08-19 14:47:31 UTC Amlenanox SmallMolecule Amlenanox is an organic compound with the chemical formula C16H14N2O4 and an average molecular weight of 298.29 g/mol. Amlenanox belongs to the 1-benzopyrans, a subclass of benzopyrans within the organic compounds. This compound is identified in seven recorded sources across several categories. Within household cleaning and consumer products, it is found in cigar cigarettes, other smoking requisites, non electric simulated smoking devices, and tobacco smoke filters. It is also present in electrical and electronic equipment, specifically electrically stimulated smoking devices. In the sector of healthcare, pharmaceuticals, and veterinary products, it is found in drugs for obstructive airway diseases and stomatological preparations. The recorded route of exposure for this substance is oral. Amlenanox interacts with five recorded protein targets. It acts as an antagonist or inhibitor of Interleukin-3 (IL3), as well as Protein S100-A12 (S100A12), Protein S100-A13 (S100A13), and Fibroblast growth factor 1 (FGF1). One additional protein target is also recorded. Amlexanox C16H14N2O4 298.2934 298.095356946 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid aphthasol 68302-57-8 CC(C)C1=CC2=C(OC3=NC(N)=C(C=C3C2=O)C(O)=O)C=C1 InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) SGRYPYWGNKJSDL-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzopyrans 1-benzopyrans Chromeno[2,3-b]pyridine-5-ones Amino acids Aminopyridines and derivatives Azacyclic compounds Benzenoids Carboxylic acids Chromenopyridines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monocarboxylic acids and derivatives Organic oxides Organooxygen compounds Organopnictogen compounds Oxacyclic compounds Primary amines Pyranones and derivatives Pyranopyridines Pyridinecarboxylic acids Vinylogous amides Amine Amino acid Amino acid or derivatives Aminopyridine Aromatic heteropolycyclic compound Azacycle Benzenoid Carboxylic acid Carboxylic acid derivative Chromeno[2,3-b]pyridine-5-one Chromenopyridine Heteroaromatic compound Hydrocarbon derivative Imidolactam Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Primary amine Pyran Pyranone Pyranopyridine Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Vinylogous amide Aromatic heteropolycyclic compounds monocarboxylic acid pyridochromene Detected and Not Quantified Amlexanox Drug Metabolism Action Pathway SMP0143455 logp 3.65 logp 2.76 ALOGPS logs -3.31 ALOGPS solubility 1.46e-01 g/l ALOGPS logp 3.65 ChemAxon pka_strongest_acidic 4.3 ChemAxon pka_strongest_basic 0.87 ChemAxon iupac 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid ChemAxon average_mass 298.2934 ChemAxon mono_mass 298.095356946 ChemAxon smiles CC(C)C1=CC2=C(OC3=NC(N)=C(C=C3C2=O)C(O)=O)C=C1 ChemAxon formula C16H14N2O4 ChemAxon inchi InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) ChemAxon inchikey SGRYPYWGNKJSDL-UHFFFAOYSA-N ChemAxon polar_surface_area 102.51 ChemAxon refractivity 81.43 ChemAxon polarizability 30.82 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72266cd2a8> DB01025 2161 BE0000125 BE0001206 BE0000885 BE0000689 BE0001120