1.0 2016-05-22 03:37:12 UTC 2026-08-18 06:42:37 UTC Amrinone SmallMolecule Amrinone is an organic compound with the chemical formula C10H9N3O and an average molecular weight of 187.20 g/mol. Amrinone belongs to the bipyridines and oligopyridines, a subclass of pyridines and derivatives within the organic compounds. It is categorized as an organoheterocyclic compound. The compound is found in or released from seven recorded sources. These include household cleaning and consumer products such as soap detergents, cigar cigarettes, tobacco smoke filters, other smoking requisites, and non electric simulated smoking devices. It is also associated with electrical and electronic equipment, specifically electrically stimulated smoking devices, as well as healthcare, pharmaceuticals, and veterinary products in the form of cardiac stimulants excluding cardiac glycosides. The recorded route of exposure for this substance is intravenous. Amrinone interacts with seven recorded protein targets. It acts as an inhibitor of tumor necrosis factor (TNF), cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A), and cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B). Additionally, it targets 3',5'-cyclic-AMP phosphodiesterase 4A (PDE4A) and three other proteins. 5-amino-1,6-dihydro-[3,4'-bipyridine]-6-one C10H9N3O 187.198 187.074561925 3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one amrinone 60719-84-8 NC1=CC(=CNC1=O)C1=CC=NC=C1 InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) RNLQIBCLLYYYFJ-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Pyridines and derivatives Bipyridines and oligopyridines Bipyridines and oligopyridines Aminopyridines and derivatives Azacyclic compounds Dihydropyridines Heteroaromatic compounds Hydrocarbon derivatives Lactams Organic oxides Organooxygen compounds Organopnictogen compounds Primary amines Pyridinones Amine Aminopyridine Aromatic heteromonocyclic compound Azacycle Bipyridine Dihydropyridine Heteroaromatic compound Hydrocarbon derivative Hydropyridine Lactam Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary amine Pyridinone Aromatic heteromonocyclic compounds Detected and Not Quantified Amrinone Drug Metabolism Action Pathway SMP0143761 logp -0.57 logp 0.27 ALOGPS logs -1.52 ALOGPS solubility 5.60e+00 g/l ALOGPS logp -0.57 ChemAxon pka_strongest_acidic 11.01 ChemAxon pka_strongest_basic 4.87 ChemAxon iupac 3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one ChemAxon average_mass 187.198 ChemAxon mono_mass 187.074561925 ChemAxon smiles NC1=CC(=CNC1=O)C1=CC=NC=C1 ChemAxon formula C10H9N3O ChemAxon inchi InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) ChemAxon inchikey RNLQIBCLLYYYFJ-UHFFFAOYSA-N ChemAxon polar_surface_area 68.01 ChemAxon refractivity 53.89 ChemAxon polarizability 18.94 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72278d1378> DB01427 3698 3570 BE0000704 BE0000436 BE0001223 BE0001133 BE0000487 BE0002353 BE0001287