1.0 2016-05-22 03:38:24 UTC 2026-08-19 09:41:40 UTC Cefaclor SmallMolecule Cefaclor is an organic compound with the chemical formula C15H14ClN3O4S and an average molecular weight of 367.81 g/mol. Cefaclor belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. The compound is identified as a beta-lactam antibacterial and an antibiotic. It functions through the inhibition of two protein targets: serine-type D-Ala-D-Ala carboxypeptidase (pbp3) and Penicillin-binding protein 1A (pbpA). Recorded exposure routes for this substance include oral and inhalation pathways. Cefaclor is found in or released from 15 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is utilized as an antibiotic and beta-lactam antibacterial. In the category of food, food processing, and cookware, it is associated with the processing of meats, the preparation of wort, and fermentation processes for beer. Sources related to household cleaning and consumer products include other smoking requisites, non-electric simulated smoking devices, and cigar cigarettes. Additionally, it is found in electrical and electronic equipment, including radio transmission systems, electrically stimulated smoking devices, electric switches, antennas, emergency protective devices, and two other sources. C15H14ClN3O4S 367.807 367.039354348 (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefaclor 53994-73-3 [H][C@]12SCC(Cl)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=O InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1 QYIYFLOTGYLRGG-GPCCPHFNSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues N-acyl-alpha amino acids and derivatives 1,3-thiazines Amino acids Aralkylamines Azacyclic compounds Azetidines Benzene and substituted derivatives Carbonyl compounds Carboximidic acids Carboxylic acids Cephems Chloroalkenes Dialkylthioethers Hydrocarbon derivatives Monoalkylamines Monocarboxylic acids and derivatives Organic oxides Organochlorides Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds Tertiary carboxylic acid amides Thiohemiaminal derivatives Vinyl chlorides Vinylogous halides Amine Amino acid Aralkylamine Aromatic heteropolycyclic compound Azacycle Azetidine Benzenoid Beta-lactam Carbonyl group Carboxamide group Carboximidic acid Carboximidic acid derivative Carboxylic acid Cephem Chloroalkene Dialkylthioether Haloalkene Hemithioaminal Hydrocarbon derivative Lactam Meta-thiazine Monocarboxylic acid or derivatives Monocyclic benzene moiety N-acyl-alpha amino acid or derivatives Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Propargyl-type 1,3-dipolar organic compound Tertiary carboxylic acid amide Thioether Vinyl chloride Vinyl halide Vinylogous halide Aromatic heteropolycyclic compounds cephalosporin Detected and Not Quantified Cefaclor Drug Metabolism Action Pathway SMP0143271 logp -2.3 logp 0.85 ALOGPS logs -3.24 ALOGPS solubility 2.10e-01 g/l ALOGPS logp -2.3 ChemAxon pka_strongest_acidic 3.03 ChemAxon pka_strongest_basic 7.44 ChemAxon iupac (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ChemAxon average_mass 367.807 ChemAxon mono_mass 367.039354348 ChemAxon smiles [H][C@]12SCC(Cl)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=O ChemAxon formula C15H14ClN3O4S ChemAxon inchi InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1 ChemAxon inchikey QYIYFLOTGYLRGG-GPCCPHFNSA-N ChemAxon polar_surface_area 112.73 ChemAxon refractivity 89.56 ChemAxon polarizability 35.11 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 5 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225970fb0> DB00833 51039 46260 BE0000576 BE0004643