1.0 2016-05-22 03:38:58 UTC 2026-08-18 15:42:55 UTC Cinoxacin SmallMolecule Cinoxacin is an organic compound with the formula C12H10N2O5 and an average molecular weight of 262.22 g/mol. Cinoxacin belongs to the benzodiazines, a subclass of diazanaphthalenes within the organic compounds. This substance is identified as an inhibitor of three protein targets: DNA topoisomerase 2-beta (TOP2B), DNA topoisomerase 2-alpha (TOP2A), and DNA gyrase subunit A (gyrA). The compound is found in or released from seven recorded sources across various sectors. In the realm of healthcare, pharmaceuticals, and veterinary products, it is used in antibiotics. Within food, food processing, and cookware, it is utilized for food preservation. Other recorded sources include household cleaning and consumer products, specifically soap detergents and tobacco smoke filters, as well as electrical and electronic equipment, including thin magnetic films, hybrid capacitors, and electrically stimulated smoking devices. Recorded exposure routes for cinoxacin include oral and inhalation pathways. C12H10N2O5 262.2182 262.05897144 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid cinoxacin 28657-80-9 CCN1N=C(C(O)=O)C(=O)C2=CC3=C(OCO3)C=C12 InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17) VDUWPHTZYNWKRN-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Diazanaphthalenes Benzodiazines Cinnolines Acetals Azacyclic compounds Benzenoids Benzodioxoles Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Pyridazines and derivatives Vinylogous amides Acetal Aromatic heteropolycyclic compound Azacycle Benzenoid Benzodioxole Carboxylic acid Carboxylic acid derivative Cinnoline Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pyridazine Vinylogous amide Aromatic heteropolycyclic compounds cinnolines oxacycle oxo carboxylic acid Detected and Not Quantified Cinoxacin Drug Metabolism SMP0130807 Cinoxacin Drug Metabolism Action Pathway SMP0143265 logp 1.72 logp 1.25 ALOGPS logs -2.44 ALOGPS solubility 9.61e-01 g/l ALOGPS logp 1.72 ChemAxon pka_strongest_acidic 4.93 ChemAxon pka_strongest_basic -4.6 ChemAxon iupac 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid ChemAxon average_mass 262.2182 ChemAxon mono_mass 262.05897144 ChemAxon smiles CCN1N=C(C(O)=O)C(=O)C2=CC3=C(OCO3)C=C12 ChemAxon formula C12H10N2O5 ChemAxon inchi InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17) ChemAxon inchikey VDUWPHTZYNWKRN-UHFFFAOYSA-N ChemAxon polar_surface_area 88.43 ChemAxon refractivity 73.6 ChemAxon polarizability 24.72 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 7 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72227b58e0> DB00827 2762 2660 BE0000366 BE0000742 BE0002425