1.0 2016-05-22 03:39:04 UTC 2026-08-25 16:54:17 UTC Clioquinol SmallMolecule Clioquinol (C9H5ClINO) is an organic compound with an average molecular weight of 305.50 g/mol. Clioquinol belongs to the haloquinolines, a subclass of quinolines and derivatives within the organic compounds. Biologically, it serves as an iron chelator (PMC13006651) and acts as an inhibitor of the Kappa-type opioid receptor (OPRK1). Regarding its health effects, it has a therapeutic effect on breast cancer (PMC9368267). The compound is found in or released from 37 recorded sources across multiple sectors. These include healthcare, pharmaceuticals, and veterinary products, where it is used in antiinfectives, antiprotozoals, gynecologicals, medicated dressings, and antiseptics and disinfectants. It is also associated with food, food processing, and cookware, specifically in food preservation and the fermentation processes for beer and the preparation of wine or sparkling wine. Other recorded sources include drinking water and water supply, building and construction materials such as roofs, floors, ceilings, fencing, and tents or canopies, as well as household cleaning and consumer products including soap detergents, perfumes within detergents and soaps, bleaching agents, cigar cigarettes, and non electric simulated smoking devices. Additionally, it is found in electrical and electronic equipment, including communication cables or conductors, antennas, electric hearing aids, auxiliary devices, and conductors or conductive bodies characterised by the conductive materials. Recorded exposure routes for clioquinol include oral, cutaneous, topical, auricular, and vaginal. Human Neurotoxin C9H5ClINO 305.5 304.910434914 5-chloro-7-iodoquinolin-8-ol clioquinol 130-26-7 OC1=C(I)C=C(Cl)C2=C1N=CC=C2 InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H QCDFBFJGMNKBDO-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Quinolines and derivatives Haloquinolines Chloroquinolines 8-hydroxyquinolines Aryl chlorides Aryl iodides Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives O-iodophenols Organochlorides Organoiodides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Pyridines and derivatives 2-iodophenol 8-hydroxyquinoline Aromatic heteropolycyclic compound Aryl chloride Aryl halide Aryl iodide Azacycle Benzenoid Chloroquinoline Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organic oxygen compound Organochloride Organohalogen compound Organoiodide Organonitrogen compound Organooxygen compound Organopnictogen compound Pyridine Aromatic heteropolycyclic compounds monohydroxyquinoline organochlorine compound organoiodine compound Detected and Not Quantified Clioquinol Drug Metabolism Action Pathway SMP0143906 logp 3.36 logp 3.66 ALOGPS logs -3.06 ALOGPS solubility 2.64e-01 g/l ALOGPS logp 3.36 ChemAxon pka_strongest_acidic 7.34 ChemAxon pka_strongest_basic 3.28 ChemAxon iupac 5-chloro-7-iodoquinolin-8-ol ChemAxon average_mass 305.5 ChemAxon mono_mass 304.910434914 ChemAxon smiles OC1=C(I)C=C(Cl)C2=C1N=CC=C2 ChemAxon formula C9H5ClINO ChemAxon inchi InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H ChemAxon inchikey QCDFBFJGMNKBDO-UHFFFAOYSA-N ChemAxon polar_surface_area 33.12 ChemAxon refractivity 60.13 ChemAxon polarizability 22.63 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb381dad0> DB04815 2788 2686 BE0000632