1.0 2016-05-22 03:39:47 UTC 2026-08-25 00:10:29 UTC Diazoxide SmallMolecule Diazoxide is an organic compound with the formula C8H7ClN2O2S and an average molecular weight of 230.67 g/mol. Diazoxide belongs to the benzothiadiazines, a subclass of thiadiazines within the organic compounds. This compound is associated with 13 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is found in antihypertensives, gynecologicals, and unclassified therapeutic products. It is also identified in food preservation within the food, food processing, and cookware category. In household cleaning and consumer products, it is present in tobacco smoke filters, perfumes within detergents and soaps, and non electric simulated smoking devices. Additionally, it is released from electrical and electronic equipment, including antennas, conductors or conductive bodies characterised by the conductive materials, electrodes, electric switches, and electrically stimulated smoking devices. Recorded exposure routes for diazoxide include oral, intravenous, and intramuscular administration. Diazoxide interacts with seven recorded protein targets. These include the inducer/inhibitor of ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), as well as mitochondrial subunits of the ATP synthase F(1) complex, specifically the beta subunit (ATP5F1B), the alpha subunit (ATP5F1A), and the delta subunit (ATP5F1D), along with three other proteins. Human Neurotoxin C8H7ClN2O2S 230.671 229.991675875 7-chloro-3-methyl-4H-1λ⁶,2,4-benzothiadiazine-1,1-dione hyperstat 364-98-7 CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2 InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) GDLBFKVLRPITMI-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Thiadiazines Benzothiadiazines 1,2,4-benzothiadiazine-1,1-dioxides Amidines Aryl chlorides Azacyclic compounds Benzenoids Hydrocarbon derivatives Imidolactams Organic oxides Organochlorides Organopnictogen compounds Organosulfonic acids and derivatives 1,2,4-benzothiadiazine-1,1-dioxide Amidine Aromatic heteropolycyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Hydrocarbon derivative Imidolactam Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organochloride Organohalogen compound Organonitrogen compound Organopnictogen compound Organosulfonic acid or derivatives Aromatic heteropolycyclic compounds benzothiadiazine organochlorine compound sulfone Detected and Not Quantified Diazoxide Drug Metabolism SMP0130712 Diazoxide Drug Metabolism Action Pathway SMP0143540 logp 1 logp 1.09 ALOGPS logs -2.62 ALOGPS solubility 5.52e-01 g/l ALOGPS logp 1 ChemAxon pka_strongest_acidic 10.48 ChemAxon pka_strongest_basic 1.33 ChemAxon iupac 7-chloro-3-methyl-4H-1λ⁶,2,4-benzothiadiazine-1,1-dione ChemAxon average_mass 230.671 ChemAxon mono_mass 229.991675875 ChemAxon smiles CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2 ChemAxon formula C8H7ClN2O2S ChemAxon inchi InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) ChemAxon inchikey GDLBFKVLRPITMI-UHFFFAOYSA-N ChemAxon polar_surface_area 58.53 ChemAxon refractivity 54.84 ChemAxon polarizability 20.98 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72764dc4f8> DB01119 3019 2911 BE0000708 BE0003841 BE0003840 BE0000484 BE0003842 BE0009097 BE0010208