1.0 2016-05-22 03:40:16 UTC 2026-08-21 21:49:11 UTC Droperidol SmallMolecule Droperidol is an organic compound with the chemical formula C22H22FN3O2 and an average molecular weight of 379.43 g/mol. Droperidol belongs to the carbonyl compounds, a subclass of organooxygen compounds within the organic compounds. It is classified under the superclass of organic oxygen compounds and the class of organooxygen compounds. The compound is identified as an antipsychotic within the category of healthcare, pharmaceuticals, and veterinary products. Its pharmacological activity involves two recorded protein targets, acting as an antagonist of the Alpha-1A adrenergic receptor (ADRA1A) and the D(2) dopamine receptor (DRD2). Recorded routes of exposure for the substance include intravenous and intramuscular administration. Droperidol is found in or released from 16 recorded sources across several sectors. In the realm of electrical and electronic equipment, it is associated with antennas, electrodes, communication cables or conductors, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices, among four other sources. Within household cleaning and consumer products, it is linked to perfumes within detergents and soaps, non electric simulated smoking devices, cigar cigarettes, and other smoking requisites. Additionally, it is recorded in relation to floors within the building and construction sector, and is used for food preservation within the food, food processing and cookware category. Human Neurotoxin C22H22FN3O2 379.4274 379.169605168 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one droperidol 548-73-2 FC1=CC=C(C=C1)C(=O)CCCN1CCC(=CC1)N1C(=O)NC2=CC=CC=C12 InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28) RMEDXOLNCUSCGS-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Alkyl-phenylketones Aryl alkyl ketones Aryl fluorides Azacyclic compounds Benzimidazoles Benzoyl derivatives Butyrophenones Fluorobenzenes Gamma-amino ketones Heteroaromatic compounds Hydrocarbon derivatives Hydropyridines N-substituted imidazoles Organic oxides Organofluorides Organopnictogen compounds Phenylbutylamines Trialkylamines Ureas Alkyl-phenylketone Amine Aromatic heteropolycyclic compound Aryl alkyl ketone Aryl fluoride Aryl halide Azacycle Azole Benzenoid Benzimidazole Benzoyl Butyrophenone Fluorobenzene Gamma-aminoketone Halobenzene Heteroaromatic compound Hydrocarbon derivative Hydropyridine Imidazole Monocyclic benzene moiety N-substituted imidazole Organic nitrogen compound Organic oxide Organofluoride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Phenylbutylamine Tertiary aliphatic amine Tertiary amine Urea Aromatic heteropolycyclic compounds aromatic ketone benzimidazoles organofluorine compound Detected and Not Quantified Droperidol Mechanism of Action Action Pathway SMP0126486 Droperidol Drug Metabolism Action Pathway SMP0142907 Droperidol Predicted Metabolism Pathway SMP0174702 logp 3.01 logp 3.93 ALOGPS logs -3.59 ALOGPS solubility 9.66e-02 g/l ALOGPS logp 3.01 ChemAxon pka_strongest_acidic 12.72 ChemAxon pka_strongest_basic 6.75 ChemAxon iupac 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one ChemAxon average_mass 379.4274 ChemAxon mono_mass 379.169605168 ChemAxon smiles FC1=CC=C(C=C1)C(=O)CCCN1CCC(=CC1)N1C(=O)NC2=CC=CC=C12 ChemAxon formula C22H22FN3O2 ChemAxon inchi InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28) ChemAxon inchikey RMEDXOLNCUSCGS-UHFFFAOYSA-N ChemAxon polar_surface_area 52.65 ChemAxon refractivity 109.52 ChemAxon polarizability 40.31 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726b88cdb0> DB00450 3168 3056 BE0000756 BE0000501