1.0 2016-05-22 03:40:28 UTC 2026-08-19 10:34:13 UTC Enoxacin SmallMolecule Enoxacin is an organic compound with the chemical formula C15H17FN4O3 and an average molecular weight of 320.32 g/mol. Enoxacin belongs to the naphthyridines, a subclass of diazanaphthalenes within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds. The compound is utilized as an antibiotic within healthcare, pharmaceuticals, and veterinary products. It has been identified in or released from 19 recorded sources. These include drinking water and water supply systems, as well as food preservation and the processing of meats. It is also associated with household cleaning and consumer products, specifically tobacco pipes, soap detergents, cigar cigarettes, pipe accessories, and tobacco smoke filters. Furthermore, it is found in electrical and electronic equipment, including amplifiers, antennas, electric hearing aids, electrically stimulated smoking devices, and conductors or conductive bodies characterized by the conductive materials. Exposure to enoxacin occurs through oral and inhalation routes. At a molecular level, enoxacin interacts with four recorded protein targets. It functions as an inhibitor of DNA gyrase subunit A (gyrA) and DNA topoisomerase 4 subunit A (parC). Additionally, it targets DNA topoisomerase 2-alpha (TOP2A) and DNA topoisomerase 2-beta (TOP2B). Human Neurotoxin C15H17FN4O3 320.3189 320.128468635 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid enoxacin 74011-58-8 CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N=C12)N1CCNCC1 InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23) IDYZIJYBMGIQMJ-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Diazanaphthalenes Naphthyridines Naphthyridine carboxylic acids and derivatives Amino acids Aminopyridines and derivatives Aryl fluorides Azacyclic compounds Carboxylic acids Dialkylamines Dialkylarylamines Fluoroquinolones Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monocarboxylic acids and derivatives N-arylpiperazines Organic oxides Organofluorides Organooxygen compounds Organopnictogen compounds Pyridinecarboxylic acids Pyridinylpiperazines Vinylogous amides 1,4-diazinane Amine Amino acid Amino acid or derivatives Aminopyridine Aromatic heteropolycyclic compound Aryl fluoride Aryl halide Azacycle Carboxylic acid Carboxylic acid derivative Dialkylarylamine Fluoroquinolone Heteroaromatic compound Hydrocarbon derivative Imidolactam Monocarboxylic acid or derivatives N-arylpiperazine Naphthyridine carboxylic acid Organic nitrogen compound Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Piperazine Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Pyridinylpiperazine Secondary aliphatic amine Secondary amine Vinylogous amide Aromatic heteropolycyclic compounds 1,8-naphthyridine derivative N-arylpiperazine amino acid fluoroquinolone antibiotic monocarboxylic acid quinolone antibiotic Detected and Not Quantified Enoxacin Drug Metabolism Action Pathway SMP0142921 logp -1 logp -0.97 ALOGPS logs -2.47 ALOGPS solubility 1.09e+00 g/l ALOGPS logp -0.98 ChemAxon pka_strongest_acidic 5.5 ChemAxon pka_strongest_basic 8.59 ChemAxon iupac 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ChemAxon average_mass 320.3189 ChemAxon mono_mass 320.128468635 ChemAxon smiles CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N=C12)N1CCNCC1 ChemAxon formula C15H17FN4O3 ChemAxon inchi InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23) ChemAxon inchikey IDYZIJYBMGIQMJ-UHFFFAOYSA-N ChemAxon polar_surface_area 85.77 ChemAxon refractivity 83.95 ChemAxon polarizability 31.63 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 7 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf3350be8> DB00467 3229 3116 BE0000366 BE0000429 BE0000742 BE0002425