1.0 2016-05-22 03:40:57 UTC 2026-05-14 16:25:13 UTC Etomidate SmallMolecule Etomidate is an organic compound with the chemical formula C14H16N2O2 and an average molecular weight of 244.29 g/mol. Etomidate belongs to the imidazoles, a subclass of azoles within the organic compounds. This compound is found in or released from five recorded sources. These include healthcare, pharmaceuticals, and veterinary products where it is used as an anesthetic, as well as household cleaning and consumer products such as bleaching agents, cigar cigarettes, and other smoking requisites. It is also associated with electrical and electronic equipment, specifically electrically stimulated smoking devices. The recorded route of exposure for this compound is intravenous. Etomidate interacts with 17 recorded protein targets. It acts as an agonist, modulator, or positive allosteric modulator of the Alpha-2B adrenergic receptor (ADRA2B), Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1), Gamma-aminobutyric acid receptor subunit delta (GABRD), and Gamma-aminobutyric acid receptor subunit pi (GABRP), in addition to 13 other proteins. Human Neurotoxin C14H16N2O2 244.289 244.121177766 ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate etomidate 33125-97-2 CCOC(=O)C1=CN=CN1C(C)C1=CC=CC=C1 InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3 NPUKDXXFDDZOKR-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Azoles Imidazoles Carbonylimidazoles Azacyclic compounds Benzene and substituted derivatives Carboxylic acid esters Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives N-substituted imidazoles Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Aromatic heteromonocyclic compound Azacycle Benzenoid Carboxylic acid derivative Carboxylic acid ester Heteroaromatic compound Hydrocarbon derivative Imidazole-4-carbonyl group Monocarboxylic acid or derivatives Monocyclic benzene moiety N-substituted imidazole Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Aromatic heteromonocyclic compounds Detected and Not Quantified Etomidate Action Pathway SMP0126127 Etomidate Drug Metabolism Action Pathway SMP0142752 Etomidate Predicted Metabolism Pathway SMP0174530 logp 2.5 logp 2.66 ALOGPS logs -2.71 ALOGPS solubility 4.77e-01 g/l ALOGPS logp 2.5 ChemAxon pka_strongest_basic 4.54 ChemAxon iupac ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate ChemAxon average_mass 244.289 ChemAxon mono_mass 244.121177766 ChemAxon smiles CCOC(=O)C1=CN=CN1C(C)C1=CC=CC=C1 ChemAxon formula C14H16N2O2 ChemAxon inchi InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3 ChemAxon inchikey NPUKDXXFDDZOKR-UHFFFAOYSA-N ChemAxon polar_surface_area 44.12 ChemAxon refractivity 69.59 ChemAxon polarizability 26.2 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226db7fa0> DB00292 36339 33418 BE0000572 BE0000795 BE0003596 BE0003599 BE0002344 BE0003592 BE0002345 BE0000471 BE0000523 BE0000381 BE0002346 BE0000478 BE0003595 BE0000764 BE0003593 BE0003594 BE0003597