1.0 2016-05-22 03:41:03 UTC 2026-08-24 16:02:11 UTC Famotidine SmallMolecule Famotidine is an organic compound with the formula C8H15N7O2S3 and an average molecular weight of 337.44 g/mol. Famotidine belongs to the thiazoles, a subclass of azoles within the organic compounds. In terms of biological activity, it acts as an antagonist of the Histamine H2 receptor (HRH2). The compound is found in or released from four recorded sources, including drinking water and water supply, electrical and electronic equipment such as antennas and amplifiers, and healthcare, pharmaceuticals and veterinary products, specifically drugs for acid related disorders. Recorded exposure routes for this substance include oral and intravenous administration. Human Neurotoxin 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide famotidin C8H15N7O2S3 337.445 337.044934829 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide famotidine 76824-35-6 NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) XUFQPHANEAPEMJ-UHFFFAOYSA-N Detected and Not Quantified Famotidine Action Pathway SMP0000231 Famotidine H2 Anti-Histamine Action Pathway SMP0126789 Famotidine Drug Metabolism Action Pathway SMP0143359 logp -2 logp -0.20 ALOGPS logs -3.10 ALOGPS solubility 2.71e-01 g/l ALOGPS logp -2 ChemAxon pka_strongest_acidic 9.29 ChemAxon pka_strongest_basic 8.38 ChemAxon iupac 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide ChemAxon average_mass 337.445 ChemAxon mono_mass 337.044934829 ChemAxon smiles NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 ChemAxon formula C8H15N7O2S3 ChemAxon inchi InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) ChemAxon inchikey XUFQPHANEAPEMJ-UHFFFAOYSA-N ChemAxon polar_surface_area 175.83 ChemAxon refractivity 80.46 ChemAxon polarizability 32.03 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 8 ChemAxon donor_count 4 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf3ec3700> DB00927 5702160 3208 BE0000112