1.0 2016-05-22 03:41:07 UTC 2026-08-18 18:40:00 UTC Fenfluramine SmallMolecule Fenfluramine is an organic compound with the formula C12H16F3N and an average molecular weight of 231.26 g/mol. Fenfluramine belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds. It acts as an agonist, antagonist, or inhibitor across seven recorded protein targets. Specifically, it is a substrate of the sodium-dependent serotonin transporter (SLC6A4), 5-hydroxytryptamine receptor 2A (HTR2A), 5-hydroxytryptamine receptor 2B (HTR2B), and 5-hydroxytryptamine receptor 2C (HTR2C), as well as three other proteins. The compound is found in or released from 17 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used in antiepileptics and antiobesity preparations, excluding diet products. It is also associated with food, food processing, and cookware, including the preparation of vinegar, food preservation, and fermentation processes for beer. Other sources include drinking water, indoor air, and household cleaning and consumer products such as tobacco smoke filters and non-electric simulated smoking devices. Additionally, it is found in electrical and electronic equipment, including electrodes, electric switches, antennas, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices, among three other items. Recorded exposure routes for fenfluramine include oral and inhalation. C12H16F3N 231.2573 231.123484132 ethyl({1-[3-(trifluoromethyl)phenyl]propan-2-yl})amine redux 458-24-2 CCNC(C)CC1=CC(=CC=C1)C(F)(F)F InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3 DBGIVFWFUFKIQN-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Phenethylamines Amphetamines and derivatives Alkyl fluorides Aralkylamines Dialkylamines Hydrocarbon derivatives Organofluorides Organopnictogen compounds Phenylpropanes Trifluoromethylbenzenes Alkyl fluoride Alkyl halide Amine Amphetamine or derivatives Aralkylamine Aromatic homomonocyclic compound Hydrocarbon derivative Organic nitrogen compound Organofluoride Organohalogen compound Organonitrogen compound Organopnictogen compound Phenylpropane Secondary aliphatic amine Secondary amine Trifluoromethylbenzene Aromatic homomonocyclic compounds (trifluoromethyl)benzenes secondary amino compound Detected and Not Quantified Fenfluramine Drug Metabolism Action Pathway SMP0143023 logp 3.47 logp 3.30 ALOGPS logs -4.03 ALOGPS solubility 2.15e-02 g/l ALOGPS logp 3.47 ChemAxon pka_strongest_basic 10.22 ChemAxon iupac ethyl({1-[3-(trifluoromethyl)phenyl]propan-2-yl})amine ChemAxon average_mass 231.2573 ChemAxon mono_mass 231.123484132 ChemAxon smiles CCNC(C)CC1=CC(=CC=C1)C(F)(F)F ChemAxon formula C12H16F3N ChemAxon inchi InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3 ChemAxon inchikey DBGIVFWFUFKIQN-UHFFFAOYSA-N ChemAxon polar_surface_area 12.03 ChemAxon refractivity 59.2 ChemAxon polarizability 22.51 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7227635fb0> DB00574 3337 3220 BE0000533 BE0000393 BE0000749 BE0000451 BE0000659 BE0000156 BE0000291