1.0 2016-05-22 03:41:24 UTC 2026-08-19 11:53:12 UTC Gliclazide SmallMolecule Gliclazide is an organic compound with the chemical formula C15H21N3O3S and an average molecular weight of 323.41 g/mol. Gliclazide belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. This compound is identified as being found in or released from 11 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is associated with gynecologicals and blood glucose lowering drugs, excluding insulins. Other sources include food preservation in food, food processing, and cookware; indoor air in air, dust, and atmospheric transport; and non-electric simulated smoking devices and tobacco smoke filters in household cleaning and consumer products. Additionally, it is linked to electrical and electronic equipment, specifically electrodes, television systems, gas filled discharge tubes with solid cathode, discharge lamps, and electrically stimulated smoking devices. Recorded exposure routes for the substance include oral and inhalation. In terms of biological activity, two protein targets have been recorded for Gliclazide. It acts as a binder or otherwise unknown interactor of ATP-binding cassette sub-family C member 8 (ABCC8) and is also associated with Vascular endothelial growth factor A, long form (VEGFA). C15H21N3O3S 323.411 323.130362243 1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea gliclazide 21187-98-4 CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1 InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19) BOVGTQGAOIONJV-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Benzenesulfonamides Aminosulfonyl compounds Azacyclic compounds Benzenesulfonyl compounds Carbonyl compounds Hydrocarbon derivatives Organic carbonic acids and derivatives Organic oxides Organopnictogen compounds Organosulfonic acids and derivatives Pyrrolidines Semicarbazides Sulfonylureas Tosyl compounds Aminosulfonyl compound Aromatic heteropolycyclic compound Azacycle Benzenesulfonamide Benzenesulfonyl group Carbonic acid derivative Carbonyl group Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfonic acid or derivatives Organosulfur compound Pyrrolidine Semicarbazide Sulfonyl Sulfonylurea Toluene Tosyl compound Aromatic heteropolycyclic compounds N-sulfonylurea Detected and Not Quantified Gliclazide Action Pathway SMP0000461 Gliclazide Action Pathway (New) SMP0126302 Gliclazide Drug Metabolism Action Pathway SMP0143541 Gliclazide Predicted Metabolism Pathway SMP0174840 logp 1.73 logp 1.52 ALOGPS logs -3.23 ALOGPS solubility 1.90e-01 g/l ALOGPS logp 1.73 ChemAxon pka_strongest_acidic 4.07 ChemAxon pka_strongest_basic 1.38 ChemAxon iupac 1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea ChemAxon average_mass 323.411 ChemAxon mono_mass 323.130362243 ChemAxon smiles CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1 ChemAxon formula C15H21N3O3S ChemAxon inchi InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19) ChemAxon inchikey BOVGTQGAOIONJV-UHFFFAOYSA-N ChemAxon polar_surface_area 78.51 ChemAxon refractivity 83.88 ChemAxon polarizability 34.22 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baef91370> DB01120 3475 3356 BE0000207 BE0000163