1.0 2016-05-22 03:42:55 UTC 2026-08-18 13:16:42 UTC Mecamylamine SmallMolecule Mecamylamine is an organic compound with the chemical formula C11H21N and an average molecular weight of 167.29 g/mol. Mecamylamine belongs to the monoterpenoids, a subclass of prenol lipids within the organic compounds. This compound is found in or released from 13 recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically antihypertensives. It is also associated with household cleaning and consumer products, including cigar cigarettes, non-electric simulated smoking devices, other smoking requisites, pipe accessories, and perfumes within detergents and soaps. Additionally, it is found in electrical and electronic equipment, such as antennas, conductors or conductive bodies characterised by the conductive materials, electrically stimulated smoking devices, electrodes, fixed capacitors and their manufacture, and one other source. The recorded route of exposure for this substance is oral. At the molecular level, mecamylamine interacts with four recorded protein targets. It functions as an antagonist of the neuronal acetylcholine receptor subunit alpha-2 (CHRNA2), neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), neuronal acetylcholine receptor subunit alpha-4 (CHRNA4), and neuronal acetylcholine receptor subunit beta-2 (CHRNB2). C11H21N 167.2911 167.167399677 N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine mecamylamine 60-40-2 CNC1(C)C2CCC(C2)C1(C)C InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3 IMYZQPCYWPFTAG-UHFFFAOYSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Bicyclic monoterpenoids Dialkylamines Hydrocarbon derivatives Organopnictogen compounds Aliphatic homopolycyclic compound Amine Bicyclic monoterpenoid Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Secondary aliphatic amine Secondary amine Aliphatic homopolycyclic compounds primary aliphatic amine Detected and Not Quantified Mecamylamine Drug Metabolism SMP0130861 Mecamylamine Drug Metabolism Action Pathway SMP0143102 logp 2.37 logp 3.13 ALOGPS logs -3.13 ALOGPS solubility 1.24e-01 g/l ALOGPS logp 2.37 ChemAxon pka_strongest_basic 10.88 ChemAxon iupac N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine ChemAxon average_mass 167.2911 ChemAxon mono_mass 167.167399677 ChemAxon smiles CNC1(C)C2CCC(C2)C1(C)C ChemAxon formula C11H21N ChemAxon inchi InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3 ChemAxon inchikey IMYZQPCYWPFTAG-UHFFFAOYSA-N ChemAxon polar_surface_area 12.03 ChemAxon refractivity 51.83 ChemAxon polarizability 20.74 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726c4028c0> DB00657 4032 5036243 BE0000738 BE0002341 BE0000849 BE0000850