1.0 2016-05-22 03:43:38 UTC 2026-08-19 12:46:38 UTC Metoprolol SmallMolecule Metoprolol is an organic compound with the formula C15H25NO3 and an average molecular weight of 267.36 g/mol. Metoprolol belongs to the tyrosols and derivatives, a subclass of phenols within the organic compounds. It acts as an inhibitor of the Beta-1 adrenergic receptor (ADRB1), Beta-2 adrenergic receptor (ADRB2), and Beta-3 adrenergic receptor (ADRB3). The compound is used as a treatment for high blood pressure (PMC10301436), heart failure (PMC11550835), hypertension (PMC11550835), atrial fibrillation (PMC1492602), arrhythmia (PMC9369816), and pheochromocytoma (PMC10074227). Recorded exposure routes include oral and intravenous administration. Metoprolol is found in or released from 17 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is identified as a beta blocking agent. It is also associated with food preservation in the category of food, food processing, and cookware, as well as drinking water and water supply. Other recorded sources include household cleaning and consumer products—specifically bleaching agents, cigar cigarettes, non electric simulated smoking devices, other smoking requisites, and perfumes within detergents and soaps—and electrical and electronic equipment, including antennas, conductors or conductive bodies characterised by the conductive materials, electric hearing aids, electric switches, and electrically stimulated smoking devices. 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol C15H25NO3 267.3639 267.183443671 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol metoprolol 51384-51-1 COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3 IUBSYMUCCVWXPE-UHFFFAOYSA-N Organic compounds Benzenoids Phenols Tyrosols and derivatives Tyrosols and derivatives 1,2-aminoalcohols Alkyl aryl ethers Dialkyl ethers Dialkylamines Hydrocarbon derivatives Organopnictogen compounds Phenol ethers Phenoxy compounds Secondary alcohols 1,2-aminoalcohol Alcohol Alkyl aryl ether Amine Aromatic homomonocyclic compound Dialkyl ether Ether Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ether Phenoxy compound Secondary alcohol Secondary aliphatic amine Secondary amine Tyrosol derivative Aromatic homomonocyclic compounds aromatic ether propanolamine secondary alcohol secondary amino compound Detected and Not Quantified Metoprolol Action Pathway SMP0000302 Metoprolol Action Pathway (New) SMP0126213 Metoprolol Drug Metabolism Action Pathway SMP0142725 logp 1.76 logp 1.80 ALOGPS logs -2.82 ALOGPS solubility 4.02e-01 g/l ALOGPS logp 1.76 ChemAxon pka_strongest_acidic 14.09 ChemAxon pka_strongest_basic 9.67 ChemAxon iupac 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol ChemAxon average_mass 267.3639 ChemAxon mono_mass 267.183443671 ChemAxon smiles COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 ChemAxon formula C15H25NO3 ChemAxon inchi InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3 ChemAxon inchikey IUBSYMUCCVWXPE-UHFFFAOYSA-N ChemAxon polar_surface_area 50.72 ChemAxon refractivity 76.7 ChemAxon polarizability 31.9 ChemAxon rotatable_bond_count 9 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7227958210> DB00264 4171 4027 BE0000694 BE0000172 BE0001012