1.0 2016-05-22 03:43:53 UTC 2026-08-22 07:27:16 UTC Mometasone furoate SmallMolecule Mometasone furoate belongs to the pregnane steroids, a subclass of steroids and steroid derivatives within the organic compounds. With an average molecular weight of 521.43 g/mol, Mometasone furoate is a heavy molecule. It has the chemical formula C27H30Cl2O6. The compound is recorded as being found in or released from eight sources. These include healthcare, pharmaceuticals, and veterinary products, specifically corticosteroids, nasal preparations, and drugs for obstructive airway diseases. Additionally, it is found in household cleaning and consumer products, including pipe accessories, non electric simulated smoking devices, and other smoking requisites, as well as electrical and electronic equipment such as television systems and antennas. Exposure routes for this substance include topical, respiratory, nasal, and intrasinal. At the molecular level, Mometasone furoate interacts with two recorded protein targets. It acts as an agonist or modulator of the glucocorticoid receptor (NR3C1) and the progesterone receptor (PGR). C27H30Cl2O6 521.429 520.141944106 (1R,2S,10S,11S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl furan-2-carboxylate nasonex 83919-23-7 [H][C@@]1(C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@]([H])(O)C[C@]2(C)[C@@]1(OC(=O)C1=CC=CO1)C(=O)CCl InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1 WOFMFGQZHJDGCX-ZULDAHANSA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Pregnane steroids Gluco/mineralocorticoids, progestogins and derivatives 11-beta-hydroxysteroids 20-oxosteroids 3-oxo delta-1,4-steroids Alkyl chlorides Alpha-chloroketones Carboxylic acid esters Chlorohydrins Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Furoic acid esters Halogenated steroids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organochlorides Oxacyclic compounds Secondary alcohols Steroid esters 11-beta-hydroxysteroid 11-hydroxysteroid 20-oxosteroid 3-oxo-delta-1,4-steroid 3-oxosteroid 9-halo-steroid Alcohol Alkyl chloride Alkyl halide Alpha-chloroketone Alpha-haloketone Aromatic heteropolycyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Chlorohydrin Cyclic alcohol Cyclic ketone Delta-1,4-steroid Furan Furoic acid ester Furoic acid or derivatives Halo-steroid Halohydrin Heteroaromatic compound Hydrocarbon derivative Hydroxysteroid Ketone Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organoheterocyclic compound Organooxygen compound Oxacycle Oxosteroid Progestogin-skeleton Secondary alcohol Steroid ester Aromatic heteropolycyclic compounds 11beta-hydroxy steroid 2-furoate ester 20-oxo steroid 3-oxo-Delta(1),Delta(4)-steroid organochlorine compound steroid ester Detected and Not Quantified Mometasone furoate Drug Metabolism Action Pathway SMP0145163 logp 5.06 logp 4.27 ALOGPS logs -4.68 ALOGPS solubility 1.08e-02 g/l ALOGPS logp 5.06 ChemAxon pka_strongest_acidic 13.84 ChemAxon pka_strongest_basic -3.3 ChemAxon iupac (1R,2S,10S,11S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl furan-2-carboxylate ChemAxon average_mass 521.429 ChemAxon mono_mass 520.141944106 ChemAxon smiles [H][C@@]1(C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@]([H])(O)C[C@]2(C)[C@@]1(OC(=O)C1=CC=CO1)C(=O)CCl ChemAxon formula C27H30Cl2O6 ChemAxon inchi InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1 ChemAxon inchikey WOFMFGQZHJDGCX-ZULDAHANSA-N ChemAxon polar_surface_area 93.81 ChemAxon refractivity 132.5 ChemAxon polarizability 52.37 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721f890c90> DB14512 441336 390091 BE0000794 BE0000557