1.0 2016-05-22 03:44:02 UTC 2026-08-20 02:23:05 UTC Nedocromil SmallMolecule Nedocromil is an organic compound with the formula C19H17NO7 and an average molecular weight of 371.34 g/mol. Nedocromil belongs to the 1-benzopyrans, a subclass of benzopyrans within the organic compounds. It is identified as a treatment for asthma (PMC11721932). The compound interacts with four recorded protein targets, acting as an antagonist or unknown agent for the fMet-Leu-Phe receptor (FPR1), Prostaglandin D2 receptor (PTGDR), Cysteinyl leukotriene receptor 1 (CYSLTR1), and Cysteinyl leukotriene receptor 2 (CYSLTR2). Nedocromil has been found in or released from eight recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it appears in nasal preparations, decongestants and antiallergics, and drugs for obstructive airway diseases. It is also associated with household cleaning and consumer products, specifically pipe accessories, cigar cigarettes, and other smoking requisites. Additionally, it is found in electrical and electronic equipment, including television systems and electrically stimulated smoking devices. Recorded exposure routes include oral, ophthalmic, and respiratory pathways, with inhalation supported by literature (PMC3152312). C19H17NO7 371.3408 371.100501903 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid nedocromil 69049-73-6 CCCC1=C2N(CC)C(=CC(=O)C2=CC2=C1OC(=CC2=O)C(O)=O)C(O)=O InChI=1S/C19H17NO7/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26) RQTOOFIXOKYGAN-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzopyrans 1-benzopyrans Chromenopyridines Azacyclic compounds Benzenoids Carboxylic acids Chromones Dicarboxylic acids and derivatives Heteroaromatic compounds Hydrocarbon derivatives Hydroquinolines Hydroquinolones Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Oxacyclic compounds Pyranones and derivatives Pyridinecarboxylic acids Quinoline carboxylic acids Vinylogous amides Aromatic heteropolycyclic compound Azacycle Benzenoid Carboxylic acid Carboxylic acid derivative Chromenopyridine Chromone Dicarboxylic acid or derivatives Dihydroquinoline Dihydroquinolone Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pyran Pyranone Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Quinoline Quinoline-2-carboxylic acid Vinylogous amide Aromatic heteropolycyclic compounds dicarboxylic acid organic heterotricyclic compound Detected and Not Quantified Nedocromil Drug Metabolism Action Pathway SMP0143160 logp 2.5 logp 2.18 ALOGPS logs -3.91 ALOGPS solubility 4.59e-02 g/l ALOGPS logp 2.5 ChemAxon pka_strongest_acidic 2.28 ChemAxon pka_strongest_basic -4.2 ChemAxon iupac 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid ChemAxon average_mass 371.3408 ChemAxon mono_mass 371.100501903 ChemAxon smiles CCCC1=C2N(CC)C(=CC(=O)C2=CC2=C1OC(=CC2=O)C(O)=O)C(O)=O ChemAxon formula C19H17NO7 ChemAxon inchi InChI=1S/C19H17NO7/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26) ChemAxon inchikey RQTOOFIXOKYGAN-UHFFFAOYSA-N ChemAxon polar_surface_area 121.21 ChemAxon refractivity 98.09 ChemAxon polarizability 36.95 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 8 ChemAxon donor_count 2 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bafc0c140> DB00716 50294 45608 BE0000705 BE0000099 BE0000296 BE0000995