1.0 2016-05-22 03:46:24 UTC 2026-08-18 09:04:21 UTC Sulfamerazine SmallMolecule Sulfamerazine is an organic compound with the chemical formula C11H12N4O2S and an average molecular weight of 264.30 g/mol. Sulfamerazine belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. In terms of biological activity, it acts as an inhibitor of the protein target dihydropteroate synthase (folP). The compound is found in or released from 11 recorded sources across various sectors. Within healthcare, pharmaceuticals, and veterinary products, it is associated with antibiotics, chemotherapy, gynecologicals, and sulfonamides and trimethoprim. In the category of household cleaning and consumer products, it is linked to perfumes within detergents and soaps, tobacco smoke filters, and non-electric simulated smoking devices. It is also found in electrical and electronic equipment, specifically electrically stimulated smoking devices and electric switches. Additionally, it is recorded in drinking water and water supply, as well as in food preservation within the food, food processing, and cookware sector. Recorded routes of exposure for this compound include inhalation and oral administration. C11H12N4O2S 264.304 264.068096338 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide sulfamerazine 127-79-7 CC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1 InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15) QPPBRPIAZZHUNT-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Aminobenzenesulfonamides Aminosulfonyl compounds Aniline and substituted anilines Azacyclic compounds Benzenesulfonyl compounds Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds Organosulfonamides Primary amines Pyrimidines and pyrimidine derivatives Amine Aminobenzenesulfonamide Aminosulfonyl compound Aniline or substituted anilines Aromatic heteromonocyclic compound Azacycle Benzenesulfonyl group Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Organosulfonic acid amide Organosulfonic acid or derivatives Organosulfur compound Primary amine Pyrimidine Sulfonyl Aromatic heteromonocyclic compounds pyrimidines sulfonamide sulfonamide antibiotic Detected and Not Quantified Sulfamerazine Drug Metabolism Action Pathway SMP0143784 Sulfamerazine Predicted Metabolism Pathway SMP0174727 logp 0.52 logp 0.44 ALOGPS logs -2.94 ALOGPS solubility 3.04e-01 g/l ALOGPS logp 0.52 ChemAxon pka_strongest_acidic 6.99 ChemAxon pka_strongest_basic 2.01 ChemAxon iupac 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide ChemAxon average_mass 264.304 ChemAxon mono_mass 264.068096338 ChemAxon smiles CC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1 ChemAxon formula C11H12N4O2S ChemAxon inchi InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15) ChemAxon inchikey QPPBRPIAZZHUNT-UHFFFAOYSA-N ChemAxon polar_surface_area 97.97 ChemAxon refractivity 68.79 ChemAxon polarizability 26.51 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226357b28> DB01581 5325 5134 BE0000803