1.0 2016-05-22 03:46:28 UTC 2026-08-25 07:47:36 UTC Sulfamethizole SmallMolecule Sulfamethizole is an organic compound with the chemical formula C9H10N4O2S2 and an average molecular weight of 270.33 g/mol. Sulfamethizole belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. In terms of biological activity, it is recorded as an inhibitor of the protein target dihydropteroate synthase (folP). The compound is found in or released from 23 recorded sources across several categories. Within healthcare, pharmaceuticals, and veterinary products, it is associated with antiinfectives, chemotherapy, gynecologicals, irrigating solutions, and sulfonamides and trimethoprim. It is also linked to food, food processing, and cookware, specifically in meat processing, food preservation, and the preparation of wort. Other recorded sources include household cleaning and consumer products, such as soap detergents, perfumes within detergents and soaps, and tobacco smoke filters. Additionally, it is found in building and construction materials, specifically roofs, as well as electrical and electronic equipment, including communication cables or conductors, antennas, coils, cores yokes or armatures, and conductors or conductive bodies characterised by the conductive materials. Recorded exposure routes for this compound include inhalation and oral ingestion. sulfamethiozole C9H10N4O2S2 270.331 270.024516964 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide sulfamethizole 144-82-1 CC1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1 InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13) VACCAVUAMIDAGB-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Aminobenzenesulfonamides Aminosulfonyl compounds Aniline and substituted anilines Azacyclic compounds Benzenesulfonyl compounds Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds Organosulfonamides Primary amines Thiadiazoles Amine Aminobenzenesulfonamide Aminosulfonyl compound Aniline or substituted anilines Aromatic heteromonocyclic compound Azacycle Azole Benzenesulfonyl group Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Organosulfonic acid amide Organosulfonic acid or derivatives Organosulfur compound Primary amine Sulfonyl Thiadiazole Aromatic heteromonocyclic compounds sulfonamide sulfonamide antibiotic thiadiazoles Detected and Not Quantified Sulfamethizole Drug Metabolism Action Pathway SMP0143025 logp 0.21 logp 0.53 ALOGPS logs -2.65 ALOGPS solubility 6.11e-01 g/l ALOGPS logp 0.21 ChemAxon pka_strongest_acidic 6.71 ChemAxon pka_strongest_basic 1.95 ChemAxon iupac 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide ChemAxon average_mass 270.331 ChemAxon mono_mass 270.024516964 ChemAxon smiles CC1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)S1 ChemAxon formula C9H10N4O2S2 ChemAxon inchi InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13) ChemAxon inchikey VACCAVUAMIDAGB-UHFFFAOYSA-N ChemAxon polar_surface_area 97.97 ChemAxon refractivity 66.84 ChemAxon polarizability 26.26 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf821c768> DB00576 5328 5137 BE0000803