1.0 2016-05-22 03:46:54 UTC 2026-08-22 11:07:05 UTC Telmisartan SmallMolecule Telmisartan (C33H30N4O2) is a compound with an average molecular weight of 514.62 g/mol. With an average molecular weight of 514.62 g/mol, Telmisartan is a heavy molecule. Telmisartan belongs to the biphenyls and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This compound is recorded as being found in or released from eight sources, including drinking water and water supply (Drinking water), healthcare, pharmaceuticals & veterinary products (Angiotensin ii receptor blockers (arbs), Lipid modifying agents), household cleaning & consumer products (Non Electric Simulated Smoking Devices, Other Smoking Requisites), and electrical & electronic equipment (Antennas, Electric Switches, Emergency Protective Devices). The recorded exposure route for the substance is oral. At the molecular level, Telmisartan acts on two recorded protein targets, serving as an antagonist/partial agonist of the Type-1 angiotensin II receptor (AGTR1) and the Peroxisome proliferator-activated receptor gamma (PPARG). These interactions contribute to various health effects and clinical applications. Specifically, Telmisartan is used as a treatment for essential hypertension (PMC4559490), hypertension (PMC6688647), diabetes mellitus (PMC7175553), and stroke (PMC7175553). Additionally, the compound is noted for having a therapeutic effect on inflammation (PMC3084581). C33H30N4O2 514.6169 514.236876224 2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid telmisartan 144701-48-4 CCCC1=NC2=C(C=C(C=C2C)C2=NC3=CC=CC=C3N2C)N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39) RMMXLENWKUUMAY-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives Biphenyls and derivatives Azacyclic compounds Benzimidazoles Benzoic acids Benzoyl derivatives Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives N-substituted imidazoles Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Aromatic heteropolycyclic compound Azacycle Azole Benzimidazole Benzoic acid Benzoic acid or derivatives Benzoyl Biphenyl Carboxylic acid Carboxylic acid derivative Heteroaromatic compound Hydrocarbon derivative Imidazole Monocarboxylic acid or derivatives N-substituted imidazole Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Aromatic heteropolycyclic compounds benzimidazoles biphenyls Detected and Not Quantified Telmisartan Action Pathway SMP0000164 Telmisartan Action Pathway (New) SMP0124969 Telmisartan Drug Metabolism Action Pathway SMP0143396 logp 6.13 logp 6.66 ALOGPS logs -5.17 ALOGPS solubility 3.50e-03 g/l ALOGPS logp 6.04 ChemAxon pka_strongest_acidic 3.65 ChemAxon pka_strongest_basic 6.13 ChemAxon iupac 2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid ChemAxon average_mass 514.6169 ChemAxon mono_mass 514.236876224 ChemAxon smiles CCCC1=NC2=C(C=C(C=C2C)C2=NC3=CC=CC=C3N2C)N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O ChemAxon formula C33H30N4O2 ChemAxon inchi InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39) ChemAxon inchikey RMMXLENWKUUMAY-UHFFFAOYSA-N ChemAxon polar_surface_area 72.94 ChemAxon refractivity 164.49 ChemAxon polarizability 58.61 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 4 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225dfb698> DB00966 65999 59391 BE0000062 BE0000215