1.0 2016-05-22 03:47:12 UTC 2026-08-19 04:53:03 UTC Tiaprofenic acid SmallMolecule Tiaprofenic acid is an organic compound with the chemical formula $\text{C}_{14}\text{H}_{12}\text{O}_3\text{S}$ and an average molecular weight of 260.31 g/mol. Tiaprofenic acid belongs to the carbonyl compounds, a subclass of organooxygen compounds within the organic compounds. The compound is identified as an inhibitor of two protein targets: Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). It is found in or released from six recorded sources across various sectors. Within healthcare, pharmaceuticals, and veterinary products, it is used in antiinflammatory and antirheumatic products. It is also associated with food preservation in the food, food processing, and cookware sector. Additionally, it is found in electrical and electronic equipment, specifically electrically stimulated smoking devices, as well as household cleaning and consumer products, including perfumes within detergents and soaps, soap detergents, and non-electric simulated smoking devices. The recorded exposure route for this compound is oral. C14H12O3S 260.308 260.05071494 2-(5-benzoylthiophen-2-yl)propanoic acid tiaprofenic acid 33005-95-7 CC(C(O)=O)C1=CC=C(S1)C(=O)C1=CC=CC=C1 InChI=1S/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,16,17) GUHPRPJDBZHYCJ-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aryl-phenylketones 2,5-disubstituted thiophenes Benzoyl derivatives Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Thiophene carboxylic acids and derivatives 2,5-disubstituted thiophene Aromatic heteromonocyclic compound Aryl-phenylketone Benzenoid Benzoyl Carboxylic acid Carboxylic acid derivative Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Monocyclic benzene moiety Organic oxide Organoheterocyclic compound Thiophene Thiophene carboxylic acid or derivatives Aromatic heteromonocyclic compounds aromatic ketone monocarboxylic acid thiophenes Detected and Not Quantified Tiaprofenic Acid Action Pathway SMP0000705 Tiaprofenic Acid Action Pathway (New) SMP0124607 Tiaprofenic acid Drug Metabolism Action Pathway SMP0143799 Tiaprofenic acid Predicted Metabolism Pathway SMP0174732 logp 3.66 logp 3.22 ALOGPS logs -3.91 ALOGPS solubility 3.24e-02 g/l ALOGPS logp 3.66 ChemAxon pka_strongest_acidic 4.03 ChemAxon pka_strongest_basic -7.8 ChemAxon iupac 2-(5-benzoylthiophen-2-yl)propanoic acid ChemAxon average_mass 260.308 ChemAxon mono_mass 260.05071494 ChemAxon smiles CC(C(O)=O)C1=CC=C(S1)C(=O)C1=CC=CC=C1 ChemAxon formula C14H12O3S ChemAxon inchi InChI=1S/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,16,17) ChemAxon inchikey GUHPRPJDBZHYCJ-UHFFFAOYSA-N ChemAxon polar_surface_area 54.37 ChemAxon refractivity 69.19 ChemAxon polarizability 26.78 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72241f3e00> DB01600 5468 5269 BE0000262 BE0000017