1.0 2016-05-22 03:47:25 UTC 2026-05-14 16:46:00 UTC Tobramycin SmallMolecule Tobramycin is an organic compound with the formula C18H37N5O9 and an average molecular weight of 467.51 g/mol. Tobramycin belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. It functions as a biological inhibitor (PMC10491871). The compound is found in or released from 27 recorded sources. These include healthcare, pharmaceuticals and veterinary products, specifically antibiotics, antiinfectives, and aminoglycoside antibacterials. Other sources include food, food processing and cookware, such as processing meats; household items, including credit card holders; building and construction materials, such as roofs, fencing, tents or canopies, and ceilings; household cleaning and consumer products, including pipe accessories, ash trays, cigar cigarettes, non electric simulated smoking devices, other smoking requisites, and one more; and electrical and electronic equipment, including antennas, auxiliary devices, electric switches, electric hearing aids, electrically stimulated smoking devices, and seven more. Recorded exposure routes for the substance include oral, intravenous, intramuscular, respiratory, ophthalmic, and inhalation. Regarding its health effects, tobramycin is used as a treatment for osteomyelitis (PMC9668588) and cystic fibrosis (PMC11773326). Additionally, it has a therapeutic effect on inflammation (PMC11664836). Human Neurotoxin C18H37N5O9 467.5145 467.259127807 (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol tobramycin 32986-56-4 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 NLVFBUXFDBBNBW-PBSUHMDJSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates 4,6-disubstituted 2-deoxystreptamines 1,2-aminoalcohols Acetals Aminocyclitols and derivatives Cyclohexanols Cyclohexylamines Hydrocarbon derivatives Monoalkylamines Monosaccharides O-glycosyl compounds Organopnictogen compounds Oxacyclic compounds Oxanes Primary alcohols 1,2-aminoalcohol 4,6-disubstituted 2-deoxystreptamine Acetal Alcohol Aliphatic heteromonocyclic compound Amine Aminocyclitol or derivatives Cyclic alcohol Cyclitol or derivatives Cyclohexanol Cyclohexylamine Glycosyl compound Hydrocarbon derivative Monosaccharide O-glycosyl compound Organic nitrogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Oxane Primary alcohol Primary aliphatic amine Primary amine Secondary alcohol Aliphatic heteromonocyclic compounds amino cyclitol glycoside Detected and Not Quantified Tobramycin Action Pathway SMP0000711 Tobramycin Action Pathway (new) SMP0126743 Netilmicin Action Pathway SMP0126750 Tobramycin Drug Metabolism Action Pathway SMP0143128 logp -6.5 logp -2.98 ALOGPS logs -0.94 ALOGPS solubility 5.37e+01 g/l ALOGPS logp -6.5 ChemAxon pka_strongest_acidic 12.54 ChemAxon pka_strongest_basic 9.83 ChemAxon iupac (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol ChemAxon average_mass 467.5145 ChemAxon mono_mass 467.259127807 ChemAxon smiles NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O ChemAxon formula C18H37N5O9 ChemAxon inchi InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 ChemAxon inchikey NLVFBUXFDBBNBW-PBSUHMDJSA-N ChemAxon polar_surface_area 268.17 ChemAxon refractivity 106.69 ChemAxon polarizability 47.18 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 14 ChemAxon donor_count 10 ChemAxon physiological_charge 5 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7222002260> DB00684 36294 33377