1.0 2016-05-22 03:50:20 UTC 2026-05-14 16:24:54 UTC 5-Aminosalicylic acid SmallMolecule 5-Aminosalicylic acid is an organic compound with the formula C7H7NO3 and an average molecular weight of 153.14 g/mol. 5-Aminosalicylic acid belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. It is utilized as an intestinal antiinflammatory agent within the category of healthcare, pharmaceuticals, and veterinary products. The compound is found in or released from 22 recorded sources. These include drinking water and water supply, ceilings in building and construction, and food, food processing and cookware, specifically in the preparation of malt, food preservation, and fermentation processes for beer. It is also associated with household cleaning and consumer products, such as bleaching agents, perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is linked to electrical and electronic equipment, including electrodes, fixed capacitors and their manufacture, antennas, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices, among 4 other sources. Recorded exposure routes for the substance are rectal and oral. At the molecular level, 5-Aminosalicylic acid interacts with 7 recorded protein targets. It acts as an agonist or inhibitor of Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). Other protein targets include Peroxisome proliferator-activated receptor gamma (PPARG), Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK), and 3 other proteins. 5-amino-2-hydroxybenzoic acid Mesalazine C7H7NO3 153.1354 153.042593095 5-amino-2-hydroxybenzoic acid mesalazine 89-57-6 NC1=CC(C(O)=O)=C(O)C=C1 InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11) KBOPZPXVLCULAV-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Aminobenzoic acids 1-hydroxy-2-unsubstituted benzenoids Amino acids Aniline and substituted anilines Benzoic acids Benzoyl derivatives Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organooxygen compounds Organopnictogen compounds Primary amines Salicylic acids Vinylogous acids p-Aminophenols 1-hydroxy-2-unsubstituted benzenoid Amine Amino acid Amino acid or derivatives Aminobenzoic acid Aminophenol Aniline or substituted anilines Aromatic homomonocyclic compound Benzoic acid Benzoyl Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Hydroxybenzoic acid Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound P-aminophenol Phenol Primary amine Salicylic acid Salicylic acid or derivatives Vinylogous acid Aromatic homomonocyclic compounds amino acid aromatic amine monocarboxylic acid monohydroxybenzoic acid phenols Detected and Not Quantified Mesalazine Action Pathway SMP0126087 Balsalazide Action Pathway SMP0126108 Olsalazine Action Pathway SMP0126110 Sulfasalazine Action Pathway SMP0126115 Mesalazine Drug Metabolism Action Pathway SMP0142705 logp -0.29 logp 0.75 ALOGPS logs -1.10 ALOGPS solubility 1.22e+01 g/l ALOGPS logp -0.29 ChemAxon pka_strongest_acidic 2.02 ChemAxon pka_strongest_basic 5.87 ChemAxon iupac 5-amino-2-hydroxybenzoic acid ChemAxon average_mass 153.1354 ChemAxon mono_mass 153.042593095 ChemAxon smiles NC1=CC(C(O)=O)=C(O)C=C1 ChemAxon formula C7H7NO3 ChemAxon inchi InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11) ChemAxon inchikey KBOPZPXVLCULAV-UHFFFAOYSA-N ChemAxon polar_surface_area 83.55 ChemAxon refractivity 40 ChemAxon polarizability 14.26 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bafd2ecf8> DB00244 4075 3933 BE0000017 BE0000262 BE0000215 BE0004655 BE0001154 BE0000248 BE0000005