1.0 2016-05-22 04:00:11 UTC 2026-08-24 11:26:10 UTC Sulfacetamide SmallMolecule Sulfacetamide is an organic compound with the formula C8H10N2O3S and an average molecular weight of 214.24 g/mol. Sulfacetamide belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. This compound is associated with 20 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used in antibiotics, antiinfectives, gynecologicals, and anti-acne preparations. In the context of food, food processing, and cookware, it is linked to food preservation, the processing of meats, and the preparation of vinegar. It is also found in household cleaning and consumer products, including perfumes within detergents and soaps, bleaching agents, cigar cigarettes, other smoking requisites, and non electric simulated smoking devices. Additionally, it is released from electrical and electronic equipment, such as electrodes, television systems, hybrid capacitors, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices. Recorded exposure routes for the compound include oral, topical, ophthalmic, vaginal, and inhalation. At the molecular level, sulfacetamide interacts with three recorded protein targets. It acts as an inhibitor of dihydropteroate synthase (folP) and targets the folic acid synthesis protein FOL1 as well as dihydropteroate synthase type-1 (sul1). N-(4-aminobenzenesulfonyl)acetamide C8H10N2O3S 214.242 214.041212886 N-(4-aminobenzenesulfonyl)acetamide sulfacetamide 144-80-9 CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11) SKIVFJLNDNKQPD-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides Aminobenzenesulfonamides Acetamides Amino acids and derivatives Aminosulfonyl compounds Aniline and substituted anilines Benzenesulfonyl compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds Organosulfonic acids and derivatives Primary amines Acetamide Amine Amino acid or derivatives Aminobenzenesulfonamide Aminosulfonyl compound Aniline or substituted anilines Aromatic homomonocyclic compound Benzenesulfonyl group Carbonyl group Carboxylic acid derivative Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organic sulfonic acid or derivatives Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfonic acid or derivatives Organosulfur compound Primary amine Sulfonyl Aromatic homomonocyclic compounds substituted aniline sulfonamide Detected and Not Quantified Sulfacetamide Drug Metabolism SMP0130933 Sulfacetamide Drug Metabolism Action Pathway SMP0143080 logp -0.26 logp 0.15 ALOGPS logs -1.71 ALOGPS solubility 4.21e+00 g/l ALOGPS logp -0.26 ChemAxon pka_strongest_acidic 4.3 ChemAxon pka_strongest_basic 2.14 ChemAxon iupac N-(4-aminobenzenesulfonyl)acetamide ChemAxon average_mass 214.242 ChemAxon mono_mass 214.041212886 ChemAxon smiles CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 ChemAxon formula C8H10N2O3S ChemAxon inchi InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11) ChemAxon inchikey SKIVFJLNDNKQPD-UHFFFAOYSA-N ChemAxon polar_surface_area 89.26 ChemAxon refractivity 52.48 ChemAxon polarizability 20.49 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf05267e0> DB00634 5320 5129 BE0000803 BE0004657 BE0004658