1.0 2016-05-22 04:18:55 UTC 2026-08-18 22:11:04 UTC Nitazoxanide SmallMolecule Nitazoxanide is an organic compound with the formula C12H9N3O5S and an average molecular weight of 307.28 g/mol. Nitazoxanide belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This compound is identified as an inhibitor and antagonist of the protein target pyruvate:ferredoxin oxidoreductase (por). It has been found in or released from seven recorded sources, including healthcare, pharmaceuticals, and veterinary products such as antiprotozoals and combinations of antibacterials. Other recorded sources include electrical and electronic equipment, specifically radio transmission systems, electric switches, and electrically stimulated smoking devices. Additionally, it is associated with household cleaning and consumer products, specifically cigar cigarettes, as well as food, food processing, and cookware, specifically the preparation of malt. The recorded exposure route for this substance is oral. C12H9N3O5S 307.282 307.026291103 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate nitazoxanide 55981-09-4 CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C(S1)[N+]([O-])=O InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17) YQNQNVDNTFHQSW-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Acylsalicylamides 2,5-disubstituted thiazoles Azacyclic compounds Benzamides Benzoyl derivatives Carbonyl compounds Carboxylic acid esters Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Nitroaromatic compounds Nitrothiazoles Organic oxides Organic oxoazanium compounds Organic zwitterions Organonitrogen compounds Organopnictogen compounds Phenol esters Phenoxy compounds Propargyl-type 1,3-dipolar organic compounds Secondary carboxylic acid amides 2,5-disubstituted 1,3-thiazole Acylsalicylamide Allyl-type 1,3-dipolar organic compound Aromatic heteromonocyclic compound Azacycle Azole Benzamide Benzoyl C-nitro compound Carbonyl group Carboxamide group Carboxylic acid derivative Carboxylic acid ester Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Nitroaromatic compound Nitrothiazole Organic 1,3-dipolar compound Organic nitro compound Organic nitrogen compound Organic oxide Organic oxoazanium Organic oxygen compound Organic zwitterion Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ester Phenoxy compound Propargyl-type 1,3-dipolar organic compound Secondary carboxylic acid amide Thiazole Aromatic heteromonocyclic compounds Detected and Not Quantified Nitazoxanide Drug Metabolism Action Pathway SMP0142959 logp 2.12 logp 2.14 ALOGPS logs -4.61 ALOGPS solubility 7.55e-03 g/l ALOGPS logp 2.12 ChemAxon pka_strongest_acidic 8.3 ChemAxon pka_strongest_basic -4.2 ChemAxon iupac 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate ChemAxon average_mass 307.282 ChemAxon mono_mass 307.026291103 ChemAxon smiles CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C(S1)[N+]([O-])=O ChemAxon formula C12H9N3O5S ChemAxon inchi InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17) ChemAxon inchikey YQNQNVDNTFHQSW-UHFFFAOYSA-N ChemAxon polar_surface_area 114.11 ChemAxon refractivity 73.89 ChemAxon polarizability 27.54 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72a91cd4a0> DB00507 41684 38037 BE0002674