1.0 2016-05-22 04:19:22 UTC 2026-05-14 19:00:35 UTC 4-Hydroxyandrostenedione SmallMolecule 4-Hydroxyandrostenedione (C19H26O3) is an organic compound with an average molecular weight of 302.41 g/mol. 4-Hydroxyandrostenedione belongs to the androstane steroids, a subclass of steroids and steroid derivatives within the organic compounds. In terms of biochemical activity, the compound is recorded as an inhibitor of the protein target Aromatase (CYP19A1). The compound is found in or released from ten recorded sources across several categories. Within the healthcare, pharmaceuticals, and veterinary products sector, it is associated with hormone antagonists and related agents. In food, food processing, and cookware, it is linked to the processing of fish. It is also found in household cleaning and consumer products, specifically within soap detergents, perfumes within detergents and soaps, tobacco smoke filters, and non-electric simulated smoking devices. Additionally, it is present in electrical and electronic equipment, including radio transmission systems, electric switches, selectors, and electrically stimulated smoking devices. The recorded route of exposure for 4-Hydroxyandrostenedione is intramuscular. (1S,2R,10R,11S,15S)-6-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-ene-5,14-dione formestane C19H26O3 302.4079 302.188194698 (1S,2R,10R,11S,15S)-6-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione (1S,2R,10R,11S,15S)-6-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione 566-48-3 [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=C(O)C(=O)CC[C@]12C InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1 OSVMTWJCGUFAOD-KZQROQTASA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Androgens and derivatives 17-oxosteroids 3-oxo delta-4-steroids Cyclohexenones Delta-4-steroids Enols Hydrocarbon derivatives Hydroxysteroids Organic oxides 17-oxosteroid 3-oxo-delta-4-steroid 3-oxosteroid 4-hydroxysteroid Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic ketone Cyclohexenone Delta-4-steroid Enol Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Aliphatic homopolycyclic compounds 17-oxo steroid 3-oxo Delta(4)-steroid enol hydroxy steroid Detected and Not Quantified Formestane Drug Metabolism Action Pathway SMP0144212 logp 3.41 logp 2.57 ALOGPS logs -3.72 ALOGPS solubility 5.78e-02 g/l ALOGPS logp 3.41 ChemAxon pka_strongest_acidic 9.21 ChemAxon pka_strongest_basic -3.7 ChemAxon iupac (1S,2R,10R,11S,15S)-6-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione ChemAxon average_mass 302.4079 ChemAxon mono_mass 302.188194698 ChemAxon smiles [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=C(O)C(=O)CC[C@]12C ChemAxon formula C19H26O3 ChemAxon inchi InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1 ChemAxon inchikey OSVMTWJCGUFAOD-KZQROQTASA-N ChemAxon polar_surface_area 54.37 ChemAxon refractivity 85.57 ChemAxon polarizability 34.07 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baec46698> DB08905 11273 10799 BE0002090