1.0 2016-05-22 04:26:11 UTC 2026-05-14 19:07:53 UTC Arbutin SmallMolecule Arbutin belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. This compound has the chemical formula $\text{C}_{12}\text{H}_{16}\text{O}_7$ and an average molecular weight of 272.25 g/mol. In biological systems, it acts as an inhibitor of the protein target tyrosinase (TYR). Industrially, arbutin is utilized as an antioxidant, a bleaching agent, and a softener and conditioner. It is found in or released from 32 recorded sources across multiple sectors. Within the electronics sector, it is associated with capacitors, cell phones, batteries, printed circuit boards, and wires and cables. In the food, food processing, and cookware sector, it is linked to food packaging, food preservation, the preparation of vinegar, the preparation of wine or sparkling wine, and fermentation processes for beer. Its presence in household cleaning and consumer products includes soap detergents, bleaching agents, perfumes within detergents and soaps, tobacco smoke filters, and non-electric simulated smoking devices. Additionally, it is found in synthetic textiles, carpets and rugs, medical devices, and building and construction materials such as sunshades awnings or outside screens. Recorded exposure routes for the compound include oral, inhalation, and touch. PFAS Phytotoxin (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol hydroquinone-O-β-D-glucopyranoside C12H16O7 272.2512 272.089602866 (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol β-arbutin 497-76-7 [H][C@]1(CO)O[C@@]([H])(OC2=CC=C(O)C=C2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Phenolic glycosides 1-hydroxy-2-unsubstituted benzenoids 4-alkoxyphenols Acetals Hexoses Hydrocarbon derivatives O-glycosyl compounds Oxacyclic compounds Oxanes Phenol ethers Phenoxy compounds Polyols Primary alcohols Secondary alcohols 1-hydroxy-2-unsubstituted benzenoid 4-alkoxyphenol Acetal Alcohol Aromatic heteromonocyclic compound Benzenoid Hexose monosaccharide Hydrocarbon derivative Monocyclic benzene moiety Monosaccharide O-glycosyl compound Organoheterocyclic compound Oxacycle Oxane Phenol Phenol ether Phenolic glycoside Phenoxy compound Polyol Primary alcohol Secondary alcohol Aromatic heteromonocyclic compounds beta-D-glucoside monosaccharide derivative Detected and Not Quantified Arbutin Drug Metabolism Action Pathway SMP0144635 logp -0.9 logp -1.36 ALOGPS logs -0.84 ALOGPS solubility 3.91e+01 g/l ALOGPS logp -0.9 ChemAxon pka_strongest_acidic 9.82 ChemAxon pka_strongest_basic -3 ChemAxon iupac (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol ChemAxon average_mass 272.2512 ChemAxon mono_mass 272.089602866 ChemAxon smiles [H][C@]1(CO)O[C@@]([H])(OC2=CC=C(O)C=C2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O ChemAxon formula C12H16O7 ChemAxon inchi InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1 ChemAxon inchikey BJRNKVDFDLYUGJ-RMPHRYRLSA-N ChemAxon polar_surface_area 119.61 ChemAxon refractivity 62.16 ChemAxon polarizability 25.88 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 7 ChemAxon donor_count 5 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7281fd5c00> DB11217 346 21241189 BE0000252