1.0 2016-05-22 04:27:57 UTC 2026-05-14 19:30:25 UTC Artemisinin SmallMolecule Artemisinin (C15H22O5) is a compound with an average molecular weight of 282.34 g/mol. Artemisinin belongs to the terpene lactones, a subclass of prenol lipids within the organic compounds. Biologically, it functions as a drug (PMC9495708), an antioxidant (PMC9495708), and an antimalarial (PMC3768262, PMC4344607). Industrially, it is used as a biocide and as a softener and conditioner. It acts as an inhibitor of the mitochondrial protein target Dihydroorotate dehydrogenase (quinone). The compound is used in the treatment of malaria (PMC11832355, PMC7793148, PMC9495708), cancer (PMC10059971), and fever (PMC7833388). Additionally, it has a therapeutic effect on polycystic ovary syndrome (PMC12947462). Artemisinin is found in or released from 22 recorded sources across several sectors. These include healthcare, pharmaceuticals & veterinary products via medical devices; drinking water & water supply via drinking water; textiles, leather & furnishings such as carpets, rugs, and synthetic textiles; household cleaning & consumer products including pipe accessories, tobacco pipes, and cigar cigarettes; food, food processing & cookware including food packaging and the preparation of vinegar, wort, and fermentation processes for beer; and electrical & electronic equipment such as batteries, capacitors, printed circuit boards, wires, cables, and cell phones, among three more sectors. Recorded routes of exposure include oral, inhalation, and touch. Human Neurotoxin PFAS Phytotoxin (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one C15H22O5 282.336 282.146723808 (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-one (+)-artemisinin 63968-64-9 [H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C(=O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4 InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 BLUAFEHZUWYNDE-NNWCWBAJSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Terpene lactones Terpene lactones Acetals Artemisinins Carbonyl compounds Carboxylic acid esters Delta valerolactones Dialkyl peroxides Hydrocarbon derivatives Monocarboxylic acids and derivatives Oxacyclic compounds Oxanes Oxepanes Trioxanes 1,2,4-trioxane Acetal Aliphatic heteropolycyclic compound Artemisinin skeleton Carbonyl group Carboxylic acid derivative Carboxylic acid ester Delta valerolactone Delta_valerolactone Dialkyl peroxide Hydrocarbon derivative Lactone Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Oxane Oxepane Sesquiterpenoid Terpene lactone Aliphatic heteropolycyclic compounds Eudesmane sesquiterpenoids Eudesmane sesquiterpenoids Sesquiterpenoids (C15) organic peroxide sesquiterpene lactone Detected and Not Quantified logp 3.11 logp 2.52 ALOGPS logs -2.35 ALOGPS solubility 1.27e+00 g/l ALOGPS logp 3.11 ChemAxon pka_strongest_basic -4.4 ChemAxon iupac (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-one ChemAxon average_mass 282.336 ChemAxon mono_mass 282.146723808 ChemAxon smiles [H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C(=O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4 ChemAxon formula C15H22O5 ChemAxon inchi InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 ChemAxon inchikey BLUAFEHZUWYNDE-NNWCWBAJSA-N ChemAxon polar_surface_area 53.99 ChemAxon refractivity 68.68 ChemAxon polarizability 29.43 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 4 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72267e7800> DB13132 68827 62060 BE0000612