1.0 2016-05-22 04:28:11 UTC 2026-08-22 04:12:58 UTC Dipyridamole SmallMolecule Dipyridamole belongs to the amines, a subclass of organonitrogen compounds within the organic compounds. With an average molecular weight of 504.63 g/mol, Dipyridamole is a heavy molecule. It has the chemical formula C24H40N8O4. In biological contexts, it serves as an antioxidant (PMC7127103). Its recorded protein targets include adenosine deaminase (ADA), cGMP-specific 3',5'-cyclic phosphodiesterase (PDE5A), 3',5'-cyclic-AMP phosphodiesterase 4A (PDE4A), and binder/inhibitor of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A), along with two other proteins. Within the realm of healthcare, pharmaceuticals, and veterinary products, the compound is used as an antithrombotic agent. It is used as a treatment for thrombosis (PMC12517424) and ischemic stroke (PMC8084398), and it has a therapeutic effect on proteinuria (PMC9368651). Recorded exposure routes include oral and intravenous administration. Additionally, Dipyridamole is found in or released from 15 recorded sources. These include food, food processing, and cookware sources such as food preservation and the preparation of vinegar. It is also found in household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Finally, it is associated with electrical and electronic equipment, specifically electrodes, electric switches, electrically stimulated smoking devices, antennas, and conductors or conductive bodies characterised by the conductive materials. Human Neurotoxin C24H40N8O4 504.6256 504.317251808 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol dipyridamole 58-32-2 OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1 InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2 IZEKFCXSFNUWAM-UHFFFAOYSA-N Organic compounds Organic nitrogen compounds Organonitrogen compounds Amines Dialkylarylamines Alkanolamines Aminopyrimidines and derivatives Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Organopnictogen compounds Piperidines Primary alcohols Alcohol Alkanolamine Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Dialkylarylamine Heteroaromatic compound Hydrocarbon derivative Imidolactam Organic oxygen compound Organoheterocyclic compound Organooxygen compound Organopnictogen compound Piperidine Primary alcohol Pyrimidine Aromatic heteropolycyclic compounds piperidines pyrimidopyrimidine tertiary amino compound tetrol Detected and Not Quantified Dipyridamole (Antiplatelet) Action Pathway SMP0000264 Dipyridamole Action Pathway SMP0122804 Dipyridamole Phosphodiesterase Action Pathway SMP0126489 Dipyridamole Drug Metabolism Action Pathway SMP0143405 logp 1.81 logp 1.52 ALOGPS logs -2.74 ALOGPS solubility 9.22e-01 g/l ALOGPS logp 1.81 ChemAxon pka_strongest_acidic 14.97 ChemAxon pka_strongest_basic 6.59 ChemAxon iupac 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol ChemAxon average_mass 504.6256 ChemAxon mono_mass 504.317251808 ChemAxon smiles OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1 ChemAxon formula C24H40N8O4 ChemAxon inchi InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2 ChemAxon inchikey IZEKFCXSFNUWAM-UHFFFAOYSA-N ChemAxon polar_surface_area 145.44 ChemAxon refractivity 142.78 ChemAxon polarizability 56.94 ChemAxon rotatable_bond_count 12 ChemAxon acceptor_count 12 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf816ef78> DB00975 3108 2997 BE0000631 BE0000182 BE0001133 BE0002214 BE0009008 BE0000925